ORGANISATION/COMPANYInserm UMR-S 1250
RESEARCH FIELDBiological sciences › BiologyMedical sciences › Medicine
RESEARCHER PROFILERecognised Researcher (R2)Established Researcher (R3)
APPLICATION DEADLINE13/11/2020 20:00 - Europe/Brussels
LOCATIONFrance › reims
TYPE OF CONTRACTTemporary
HOURS PER WEEK40
OFFER STARTING DATE01/02/2021
The successful candidate will work on a project (Research program and interventions to reduce and fight against tobacco consumption) funded by the Research Institute in Public Health (Institut de Recherche en Santé Publique, IReSP) and the French National National Cancer Institute (Institut National du Cancer, INCa): “Physiopathologic implication of human nicotinic receptor polymorphism to Chronic Obstructive Pulmonary Disease and their exacerbations”.
We seek highly motivated candidates with interests in pathogenesis, cellular plasticity, and genetics. Candidates having a good working knowledge in human primary cell cultures, molecular biology (PCR and WB), microscopy and image analysis, and bioinformatics analysis will be highly considered (but not required). We strongly value team spirit and a positive work environment.
Qualifications, experience and skills also include the development, design and execution of key experiments to achieve objectives; reading and intellectual contribution to produce scientific communications; help/coach junior scientists (master and PhD students); scientific rigor and strong communicational skills to drive external collaborations; draft and writing of scientific manuscripts. Required languages: French/English: excellent.
Please contact Dr Valérian Dormoy and Pr Gaëtan Deslée by email. Interested applicants should send a CV, letter of motivation, and the contact information of at least 2 referees to firstname.lastname@example.org and email@example.com
- Diabasana Z et al. Nicotinic receptor subunits atlas in the adult human lung. Int J Mol Sci. 2020, 21(20), 7446. doi: 10.3390/ijms21207446.
- Maskos U. The nicotinic receptor alpha5 coding polymorphism rs16969968 as a major target in disease: Functional dissection and remaining challenges. J Neurochem. 2020 Aug;154(3):241-250. doi: 10.1111/jnc.14989.
- Perotin JM et al. Managing patients with chronic cough: challenges and solutions. Ther Clin Risk Manag. 2018 Jun 6;14:1041-1051. doi: 10.2147/TCRM.S136036.
- Le Rouzic O et al. Th17 cytokines: novel potential therapeutic targets for COPD pathogenesis and exacerbations. Eur Respir J. 2017 Oct 12;50(4):1602434. doi: 10.1183/13993003.02434-2016.
- Medjber K et al. Role of nicotinic acetylcholine receptors in cell proliferation and tumour invasion in broncho-pulmonary carcinomas. Lung Cancer. 2015 Mar;87(3):258-64. doi: 10.1016/j.lungcan.2015.01.001.
EURAXESS offer ID: 568513
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