3-years postdoctoral position in precision cellular immunotherapy

A 3-years postdoctoral position is available at the Lille University Hospital (CHU Lille) and INSERM UMR1277, Lille France in precision cellular immunotherapy. This is part of a highly collaborative project led by Dr. Suman Mitra, Pr. Jos Melenhorst and Pr. Franck Morschhauser. The candidate will work in Dr. Suman Mitra’s group at INSERM 1277 Lille and CHU de Lille in close collaboration with Prof. Jos Melenhorst at the Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania. The candidate will have a terminal degree (PhD, MD, DVM). The candidate should be willing to travel and will spend time both in USA and France. She or he will work under the guidance of Prof. Melenhorst and Suman Mitra assume responsibility for specific projects focused on dissecting the immunobiology of chimeric antigen receptor (CAR) T cell therapies for Non-Hodgkin’s Lymphoma. This is truly a translational research project with the goal to identify novel mechanisms-based biomarkers of therapeutic response and failure of CAR-T therapy in Non-Hodgkin lymphoma. This is a highly collaborative project led by dept of hematology Lille (Prof. Franck Morschhauser, Ibrahim Yakoub Agha), Suman Mitra (Inserm 1277 Lille) and Prof. Jos Melenhorst (UPenn).

The position will involve DNA and RNA sequencing, flow cytometry and other advanced single cell proteomics and transcriptomics approaches, gene modifications of T cells using lentiviral or other vectors. The position will serve to extend, refine, and enhance skills necessary for professional and career development. Furthermore, this position will enable the candidate to broaden her/his scientific background by acquiring new research capabilities. The candidate is expected to conduct research independently, prioritize and multitask, and thrive in a highly collaborative environment in both Upenn and Lille. She or He will have the opportunity to build working relationships with leading clinicians and scientists to broaden scientific knowledge and skills. The candidate will spend significant amount of time at the Melenhorst laboratory, USA and is also expected to travel to Lille, France, to set up the bioanalytical pipeline in the Mitra lab. The post-doc is furthermore expected to participate in and take ownership of project planning, the development of experimental procedures and maintaining their laboratory notebook, plus data analysis and the communication of their results at laboratory, department, and scientific meetings, and via summarizing his/her data in progress reports and manuscripts. The post-doc is also expected to acquire the technical skills, contribute to laboratory management, budget management, and grant writing. Further, the post-doctoral fellow is expected to train and supervise junior lab members and be an effective team member. The position is available immediately.