ORGANISATION/COMPANYUniversity of Pennsylvania
RESEARCH FIELDBiological sciences › BiologyBiological sciences › Other
RESEARCHER PROFILERecognised Researcher (R2)
APPLICATION DEADLINE18/11/2020 00:00 - Europe/Brussels
LOCATIONUnited States › Philadelphia
TYPE OF CONTRACTTemporary
HOURS PER WEEK38
Postdoctoral fellow positions at Penn Epigenetics Institute and the Institute for Immunology: Philadelphia, PA, United States
A postdoctoral position funded by Chan Zuckerberg Initiative award for a computational biologist is available at the University of Pennsylvania in laboratories of Drs. Vahedi and Henao-Mejia.
Childhood obesity is one of the most important global public health challenges of the 21st century worldwide. The goal of this multidisciplinary collaboration is to map the impact of obesity in the immune system in children and the long-term immunological consequences of this disorder. As inflammation plays a critical role in the majority of obesity associated diseases, our research will be the first step to elucidate alterations in the immune system that contribute to disease progression in obese children using single-cell technologies.
The Vahedi laboratory is part of the Department of Genetics, Perelman School of Medicine at the University of Pennsylvania. We are a core member of the Epigenetics Institute (https://goo.gl/GnaZdx) and a member of the Institute for Immunology (https://goo.gl/Vi2jAP). The Vahedi laboratory is multidisciplinary, integrating computational and experimental approaches to develop a system-level understanding of gene regulation in immune cells. We use bulk assays including ChIP-seq, ATAC-seq, and chromatin conformation assays such as HiC, in addition to cutting-edge single-cell genomic assays such as single-cell (sc)ATAC-seq and scRNA-seq or the single-cell Oligopaint imaging technique.
The Henao-Mejia laboratory is part of the Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania and the Children’s Hospital of Philadelphia. We are a member of the Institute for Immunology (https://goo.gl/Vi2jAP) and the Institute for Diabetes, Obesity and Metabolism (https://www.med.upenn.edu/idom/). The Henao-Mejia laboratory integrates cellular and molecular immunology experimental approaches as well as CRISPR/Cas9 technologies to elucidate the mechanisms of acute and chronic inflammation. In addition, Dr. Henao-Mejia is the Scientific Director of the CRISPR/Cas9 mouse targeting core at Penn, which is embedded in the Henao-Mejia lab.
Computational candidates are required to hold a PhD in computer science, engineering, bioinformatics or related programs. Trainees with experience in single-cell genomics are encouraged to apply. Expertise in machine learning and statistics in addition to programing in Python and R in a Unix environment is required.
Additional postdoctoral opportunities for wet and dry biologists are available in both laboratories of Drs. Henao-Mejia and Vahedi. Experimental candidates are required to hold a PhD in molecular biology, immunology, or biochemistry. Experience in genomics and epigenomics will be viewed favorably. Potential training opportunities exist for the experimental scientist joining our lab to learn computational genomics.
Further information about our labs could be found at http://vahedilab.github.io/LabSite/
Interested applicants should submit a CV to email@example.com
EURAXESS offer ID: 551436
Posting organisation offer ID: 147575
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