ORGANISATION/COMPANYLMU University Munich
RESEARCH FIELDMedical sciences › Medicine
RESEARCHER PROFILEFirst Stage Researcher (R1)
APPLICATION DEADLINE24/08/2020 17:00 - Europe/Brussels
LOCATIONGermany › München
TYPE OF CONTRACTTemporary
The Steffens Lab at the Institute of Cardiovascular Prevention, Ludwig-Maximilians-University in Munich is looking for a PhD student to study the "Mechanisms of pericardial adipose tissue inflammation in the context of myocardial infarction"
Brief project description:
We recently found that the pericardial adipose tissue contains a high density of lymphocyte-rich immune cell clusters. In response to myocardial infarction, lymphocytes within the clusters expand and secrete cytokines, thereby affecting the cardiac infarction healing (Horckmans et al. Circulation 2018). The aim of the PhD project is to study how the pericardial adipose tissue senses cardiac injury, and what are the factors leading to the activation of immune cells within pericardial lymphoid clusters.
The project involves experimental mouse models of myocardial infarction, combined with state-of-the art technologies, including high-resolution imaging from nanoscopic scale to entire tissue, bulk or single cell RNA-seq and multi-panel flow cytometry.
Our international and interdisciplinary team is part of larger research consortia, in particular the DFG-funded CRC1123 and German Center for Cardiovascular Research (DZHK), located at the institute of Cardiovascular Prevention, which provides an excellent infrastructure.
The PhD student will be enrolled in the Integrated Graduate School of SFB 1123 (www.sfb1123.med.uni-muenchen.de/index.html) that offers a three-year structured PhD program to obtain a PhD in Medical Research. Our structured PhD training program consisting of advanced methodological courses with a major focus on bioimaging tools, basic principle and soft skills seminars, lecture series, and annual retreats. The position is funded for at least three years, according to the DFG guidelines.
Eligible candidates should have experience with mouse models, immunological and molecular biological techniques, a strong motivation and team spirit. German language skills would be helpful but not required, whereas solid English skills written and spoken (EU level B2 or equivalent) are mandatory. The successful candidate should hold an above-average master degree in biological sciences or related fields.
Interested candidates should submit their application (including CV, publication list and email contacts of 2 references as single PDF) via email to: firstname.lastname@example.org
The Ludwig- Maximilians-University (LMU) in Munich, Germany, is recognized as one of Europe's premier academic and research institutions. In the Times Higher Education World Reputation Ranking 2019, LMU is ranked 43rd and represents Germany’s most highly regarded university. As part of the German federal and state governments’ Excellence Strategy, LMU has been awarded funding as University of Excellence. Hence, the LMU is particularly noted for providing excellent conditions for innovative research.
Required Research Experiences
RESEARCH FIELDMedical sciences
YEARS OF RESEARCH EXPERIENCE1 - 4
RESEARCH FIELDBiological sciences
YEARS OF RESEARCH EXPERIENCE1 - 4
REQUIRED EDUCATION LEVELBiological sciences: Master Degree or equivalentChemistry: Master Degree or equivalentMedical sciences: Master Degree or equivalent
REQUIRED LANGUAGESENGLISH: Excellent
experience with mouse models, immunological and molecular biological techniques
solid English skills written and spoken (EU level >B2 or equivalent)
EURAXESS offer ID: 540894
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