ORGANISATION/COMPANYIdex université Grenoble Alpes
RESEARCH FIELDBiological sciences › BiologyComputer science › InformaticsMathematics
RESEARCHER PROFILEFirst Stage Researcher (R1)Recognised Researcher (R2)Established Researcher (R3)Leading Researcher (R4)
APPLICATION DEADLINE05/07/2020 00:00 - Europe/Brussels
LOCATIONFrance › Grenoble
TYPE OF CONTRACTTemporary
OFFER STARTING DATE01/10/2020
Lectins are proteins that interact non-covalently with carbohydrates reversibly and specifically while displaying no catalytic or immunological activity. Lectins are thought to have the ability to decipher the glycocode, i.e., the structural information present on complex carbohydrates at the cell surface. Lectins are involved in many biological processes, their interactions with carbohydrates often play an essential role to the onset, detection, and potentially prevention of human diseases such as cancer, inflammation, diabetes, neurodegenerative diseases and bacterial and viral infection. The UniLectin portal is composed of different modules encompassing UniLectin3D, a database with more than 2000 3D-structures of lectins and LectinPred, a prediction tool based on the lectin structure classification to screen available genomes.
Further development of the UniLectin platform is challenged in two domains: i/ content and usability: improvement is expected from extending lectin coverage, and adding new modules and ii/ outreach and integration: UniLectin tools should be used more widely in several communities, such as microbiologists or biochemists and integrated in a larger variety of other bioinformatics resources. The project includes extending the sequence coverage of lectins, modeling carbohydrate binding domains in the new lectins predicted in genomes, predicting specificity towards complex oligosaccharides, and improving lectin domain annotation.
Funding category: Contrat doctoral
International strategic partnership
PHD title: PhD position in glycobioinformatics
PHD Country: France
Restriction or constraints related to the position
Mobility after 18 months and monthly visits to the other laboratory.
Expected skills :
- Trade skills/ expertise
- Personal skills
The candidate should be able to interact with two different teams, working in different domains. Adaptability, sociability and eagerness to learn will be key requirements, as well as being able to work independently.
Previous formation, diplomas:
The candidate should hold a master or engineering degree or any equivalent qualifications
- Motivation letter and Statement of purpose
- Copy of last diploma and notes of the two last years
- Curriculum vitae
- References (at least two)
EURAXESS offer ID: 530336
Posting organisation offer ID: 92447
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