RESEARCHER PROFILEFirst Stage Researcher (R1)
APPLICATION DEADLINE01/08/2020 23:59 - Europe/Brussels
LOCATIONBelgium › Leuven
TYPE OF CONTRACTTo be defined
HOURS PER WEEK38
Airway hyper reactivity (AHR) is a common clinical feature of both upper and lower airway inflammation, characterized by mucosal responses to environmental stimuli that do not evoke responses in healthy individuals. Airway hyper reactivity is the result of increased sensitivity of afferent neurons in the airways to cold air, pollutants and/or bacterial components. However, the mechanisms responsible for AHR are not well understood. Thanks to the development of single cell RNA sequencing, a novel epithelial cell type, i.e. neuro endocrine cells, have been described in the airways. These cells are equipped with chemo sensors that can be activated by pollutants, cold air and bacterial components. The role of these cells in non-allergic airway diseases, and whether these cells contribute to AHR has not been explored. The goal of this project is to explore the role of these newly identified neuro endocrine cells in the pathology of non-allergic airway diseases, and their contribution to AHR.
We offer:• a full time appointment (100%) as a PhD student for a period of 4 years, of which the first three years are covered by internal research funding (3M180292) and the fourth year by the hosting research group. In the meantime, the candidate will be encouraged to apply for an FWO doctoral mandate. • Membership of a world-renowned laboratory in airway diseases, as part of a motivated interdisciplinary team, with an extensive international network. • The possibility to participate and present own research at national and international conferences
• Master’s degree (with high grades) in Medicine, Biomedical Sciences, Bio-engineering or similar • An inquisitive and creative mind, good problem-solving skills• Ambition to start and engage in research, with perseverance to bring the PhD project to a successful defense of the PhD project at KU Leuven• Proven proficiency in English, both written and orally• Strong writing and analytical skills• Good communication and organization skills• Ability to meet deadlines • Capacity to work both as an independent researcher and as part of a team• Team player
For more information please contact Mr. Brecht Steelant, tel.: +32 16 32 19 16, mail: firstname.lastname@example.org or Prof. dr. Peter Hellings, tel.: +3216332342, mail: email@example.com.
You can apply for this job no later than 01/08/2020 via the online application tool
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EURAXESS offer ID: 508405
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