27/02/2020

Postdoc position – Computational modeling of limb development

This job offer has expired


  • ORGANISATION/COMPANY
    KU Leuven
  • RESEARCH FIELD
    EngineeringBiomedical engineering
    EngineeringMechanical engineering
    MathematicsApplied mathematics
    PhysicsBiophysics
    PhysicsComputational physics
  • RESEARCHER PROFILE
    Recognised Researcher (R2)
  • APPLICATION DEADLINE
    27/03/2020 22:00 - Europe/Athens
  • LOCATION
    Belgium › Leuven
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    38

Fascination with pattern formation in living organisms is millennia old.One of the biological models to investigate this process is the developing limb. Our understanding of limb development has progressed greatly over the last half century. However, the intricate interactions between biochemical (e.g. genes, proteins) and biophysical (e.g. cell-cell interactions) factors become too complex to be understood without the help of computational modeling. In a recently awarded, 4-year research proposal, MatheMorphosis, we aim to follow an integrative approach to study the biophysical and biochemical regulation of limb development. We will continue our development of a multiscale multiphysics agent-based model of the early stages of limb development, exploring various ways to optimize, validate and question the model and its predictions. This will be combined with a strong experimental research track based on the recombinant limb technique in the chick

For the in silico track of this project, we search a candidate for a postdoc position with a background in systems biology and/or computational modeling of biological systems. The postdoc will design and improve a dynamic agent-based simulation of the early limb development, especially focusing on the coupling of the cell-level with the intra-cellular signaling part. The postdoc will perform simulations and compare its results with experimental data, generated by the other researchers of the project.

The candidate has a PhD or equivalent doctoral degree in either (bio)physics / mathematics or mechanical engineering with a strong interest in systems biology or a degree in systems biology/quantitative biology with a strong interest in the mechanical description of cellular interactions. The candidate must have proven experience in (mechanical) modeling. Knowledge of Python and C++  programming is a definite plus as these are the languages used in the computational platform of the MatheMorphosis project.. Familiarity with agent-based modeling techniques is desirable.

Selection process

The vacancy will remain open until filled. Candidates are required to send their dossier composed of a CV, motivation letter and contact details of 2 referees via email to bart.smeets@kuleuven.be and liesbet.geris@kuleuven.be

Web site for additional job details

Required Research Experiences

  • RESEARCH FIELD
    EngineeringBiomedical engineering
  • YEARS OF RESEARCH EXPERIENCE
    4 - 10
  • RESEARCH FIELD
    EngineeringMechanical engineering
  • YEARS OF RESEARCH EXPERIENCE
    4 - 10
  • RESEARCH FIELD
    MathematicsApplied mathematics
  • YEARS OF RESEARCH EXPERIENCE
    4 - 10
  • RESEARCH FIELD
    PhysicsBiophysics
  • YEARS OF RESEARCH EXPERIENCE
    4 - 10

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Engineering: PhD or equivalent
    Mathematics: PhD or equivalent
    Physics: PhD or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Good

Skills/Qualifications

The candidate has a PhD or equivalent doctoral degree in either (bio)physics / mathematics or mechanical engineering with a strong interest in systems biology or a degree in systems biology/quantitative biology with a strong interest in the mechanical description of cellular interactions. The candidate must have proven experience in (mechanical) modeling. Knowledge of Python and C++ programming is a definite plus as these are the languages used in the computational platform of the MatheMorphosis project.. Familiarity with agent-based modeling techniques is desirable.

Map Information

Job Work Location Personal Assistance locations
Work location(s)
1 position(s) available at
KU Leuven
Belgium
Leuven
3000

EURAXESS offer ID: 498446

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