02/02/2020
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Early Stage Researcher/PhD Position in biomechanics: Personalized Ultrasound-based hemodynamics simulations in the diseased abdominal aorta

This job offer has expired


  • ORGANISATION/COMPANY
    Ecole Nationale Supérieure des Mines de Saint Etienne
  • RESEARCH FIELD
    EngineeringBiomedical engineering
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    02/03/2020 22:00 - Europe/Brussels
  • LOCATION
    Multiple locations, see work locations below.
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    15/03/2020
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • REFERENCE NUMBER
    MeDiTATe-ESR14
  • MARIE CURIE GRANT AGREEMENT NUMBER
    859836

OFFER DESCRIPTION

Keywords: biomechanics, Aneurysm; Multi-Physics Simulation; Patient-specific Models, hemodynamics, fluid structure interactions, SPH.

 

General framework: 14 Early Stage Researchers (ESRs) will be offered doctoral positions as part of the MeDiTATe project, which is funded through the H2020 program: Marie Skłodowska-Curie Actions (MSCA) Innovative Training Networks – European Industrial Doctorate. The whole MeDiTATe project aims to develop state-of-the-art image based medical Digital Twins of cardiovascular districts for a patient specific prevention and treatment of aneurysms. The individual research projects of each ESR within MeDiTATe are defined across five research tracks:

(1) High fidelity CAE multi-physics simulation with RBF mesh morphing (finite-element modeling, fluid structure interactions…)

(2) Real time interaction with the digital twin by Augmented Reality, Haptic Devices and Reduced Order Models

(3) HPC tools, including GPUs, and cloud-based paradigms for fast and automated CAE processing of clinical database

(4) Big Data management for population of patients imaging data and high fidelity CAE twins

(5) Additive Manufacturing of physical mock-up for surgical planning and training to gain a comprehensive Industry 4.0 approach in a clinical scenario (Medicine 4.0)

The work of each ESR, hired for two 18 months periods (industry + research) and enrolled in PhD programmes, will be driven by the multi disciplinary and multi-sectoral needs of a multi-disciplinary research consortium (clinical, academic and industrial) which will offer the expertise of Participants to provide scientific support, secondments and training. Recruited researchers will become active players of a strategic sector of the European medical and simulation industry and will face the industrial and research challenges daily faced by clinical experts, engineering analysts and simulation software technology developers.

During their postgraduate studies they will be trained by the whole consortium receiving a flexible and competitive skill-set designed to address a career at the cutting edge of technological innovation in healthcare. The main objective of MeDiTATe is the production of high-level scientists with a strong experience of integration across academic, industrial and clinical areas, able to apply their skills to real life scenarios and capable to introduce advanced and innovative digital twin concepts in the clinic and healthcare sectors.

 

Objectives: The research of this ESR will address the issue of estimating non-invasively hemodynamics descriptors in the aorta, such as 3D flow field and internal aortic pressure. The estimations will be based on coupling numerical simulation with dynamic Doppler acquisitions of patients with abdominal aortic aneurysms (AAA), enabling the measurements of partial flow velocities in the aneurysms. Accessing these hemodynamics descriptors is non-trivial, although it would enable to build a complete 3D flow map, thanks to the integration of physical principles, using a numerical solver. These hemodynamics parameters can then be used to support the characterization of the arterial wall or the prediction of wall remodelling and intraluminal thrombus (ILT) deposition. Eventually, these 3D flow field maps and patterns will greatly serve to progress in the global understanding of evolution of arterial wall degradation.

 

Description of the ESR project:

The ESR will be enrolled in the PhD programme of University of Lyon at Mines Saint-Etienne, France. The PhD thesis will take place at 3 different places:

- Mines Saint-Etienne (France) in the CIS department, which conducts major international research projects in the field of soft tissue biomechanics, in particular aortic aneurysms. He will collaborate with other researchers involved in ERC projects (https://www.mines-stetienne.fr/en/author/avril/, https://www.emse.fr/~badel/).

- Philips France SAS – Paris (France) which has an image processing competence centre with strong focus on clinical applications. Its mission is to design innovative image enhancement/analysis algorithms and implement them in an efficient way meeting constraints of commercial products. Philips was a pioneer in 3D Ultrasound, being first to introduce a matrix probe, and Philips Research Paris provided the first quantification tools for analysing vascular volumes.

- Fondazione Toscana G. Monasterio (Italy) is a public entity specialized in healthcare and research activities in the field of cardiology, cardio-surgery, electrophysiology and for the treatment of cardiopulmonary diseases, included rare disorders such as congenital heart defects. It was involved was involved in several projects involving big data analysis, numerical simulation and image processing.

 

Benefits, salary and duration:

The selected candidate will receive a salary in accordance with the MSCA regulations for ESR. The gross salary includes a living allowance (€3,270 per month, subject to MSCA country correction coefficient, i.e. 115.7% for France and 104.4% for Italy), a mobility allowance (€600 per month), and a family allowance (€500 per month, if the researcher has family by the date of recruitment, regardless of whether the family will move with the researcher or not). The guaranteed funding is for 36 months (i.e. EC funding).

 

Eligibility criterion:

Applicants can be of any nationality. They need to fully respect both eligibility criteria (to be demonstrated in the Europass CV): (a) Early-Stage Researchers (ESRs) must, at the date of recruitment by the beneficiary, be in the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree. (b) Conditions of international mobility of researchers: Researchers are required to undertake trans-national mobility (i.e. move from one country to another) when taking up the appointment. At the time of selection by the host organization, researchers must not have resided or carried out their main activity (work, studies, etc.) in France for more than 12 months in the 3 years immediately prior to their recruitment. Short stays, such as holidays, are not taken into account.

 

Candidate profile: Candidates with strong skills in fluid mechanics (modeling and experimental) and numerical techniques. Initial knowledge on SPH would be appreciated. Motivation and interest in bioengineering applications is recommended.

 

How to apply: Send CV, cover letter, BSc and MSc degrees, and letters of recommendation to s.celi@ftgm.it, hernan.morales@philips.com, laurence.rouet@philips.com and avril@emse.fr.

More Information

Benefits

The selected candidate will receive a salary in accordance with the MSCA regulations for ESR. The gross salary includes a living allowance (€3,270 per month, subject to MSCA country correction coefficient, i.e. 115.7% for France and 104.4% for Italy), a mobility allowance (€600 per month), and a family allowance (€500 per month, if the researcher has family by the date of recruitment, regardless of whether the family will move with the researcher or not). The guaranteed funding is for 36 months (i.e. EC funding).

 

Eligibility criteria

 

Applicants can be of any nationality. They need to fully respect both eligibility criteria (to be demonstrated in the Europass CV): (a) Early-Stage Researchers (ESRs) must, at the date of recruitment by the beneficiary, be in the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree. (b) Conditions of international mobility of researchers: Researchers are required to undertake trans-national mobility (i.e. move from one country to another) when taking up the appointment. At the time of selection by the host organization, researchers must not have resided or carried out their main activity (work, studies, etc.) in France for more than 12 months in the 3 years immediately prior to their recruitment. Short stays, such as holidays, are not taken into account.

Offer Requirements

Skills/Qualifications

 

Candidates with strong skills in fluid mechanics (modeling and experimental) and numerical

techniques. Initial knowledge on SPH would be appreciated. Motivation and

interest in bioengineering applications is recommended.

 

 

 

Work location(s)
1 position(s) available at
Philips
France
Paris
1 position(s) available at
Ecole Nationale Supérieure des Mines de Saint Etienne
France
Saint-Etienne
1 position(s) available at
Fondazione Toscana Gabriele Monasterio
Italy
Massa

Open, Transparent, Merit based Recruitment procedures of Researchers (OTM-R)

Know more about it at Ecole Nationale Supérieure des Mines de Saint Etienne

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EURAXESS offer ID: 487929

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