15/10/2019
Marie Skłodowska-Curie Actions

15 PhD positions in Marie Sklodowska Curie ITN “Active Monitoring of Cancer As An Alternative To Surgery” (CAST)


  • ORGANISATION/COMPANY
    ACADEMISCH ZIEKENHUIS LEIDEN (LUMC)
  • RESEARCH FIELD
    Medical sciencesMedicine
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    31/10/2020 17:00 - Europe/Brussels
  • LOCATION
    Multiple locations, see work locations below.
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/11/2019
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • MARIE CURIE GRANT AGREEMENT NUMBER
    857894
  • IS THE JOB RELATED TO STAFF POSITION WITHIN A RESEARCH INFRASTRUCTURE?
    Yes

15 PhD Positions

 

are available within the

 

Marie Skłodowska Curie Innovative Training Network on

 

Active monitoring of Cancer AS An AlternaTive To Surgery - CAST

 

 

CAST (www.cast-cancer.eu) is a Marie Skłodowska Curie Innovative Training Network funded by the European Commission.

 

When a patient is discovered to have cancer, one of the primary goals is to have the tumour removed by surgery. Although this provides excellent oncological control,

it is associated with morbidity and functional problems in cancer survivors.

Recent studies have shown that the immediacy to perform a resection does not always lead to improved clinical outcome.

Furthermore, cancer surgery can often lead to complications where the quality of life for the patient is compromised by toxic side effects and /or damage to

waiting, active monitoring or surveillance, which are terms used to describe a monitoring strategy for cancer.

The concept may be antithetical but the functional advantage of these

alternatives is clear even though there is some concern about the risk.

Though the evidence is still weak, current studies suggest that with adequate selection and follow-up, this oncological risk is small.

A major consideration for clinicians is now to maintain quality of life for all patients.

Our objective in this proposal is to implement novel approaches so that cancer surgery can be avoided, where we aim to

(a) develop new monitoring technologies from industry so that the surveillance window can be increased to allow for better treatment options over time and to avoid surgery,

(b) develop new ‘watch and wait’ strategies in order to study the behaviour of the cancer so that any risks to the patient can be minimised leading to a better clinical outcome and (c) train a new generation of preclinical and clinical scientists to be able to implement this new concept as standard of care and to maximise the benefits of an active monitoring policy.

 

We will provide a structured 3-year cutting-edge PhD training programme in and beyond the fields of cancer and its biological basis, surgery, diagnostic tools (e.g. genetic, molecular diagnostic), medical physics and optical physics.

The earliest starting date will be November 1st, 2019. The latest will be October 31st September 2020.

 

We are looking for highly motivated and talented PhD students holding a Master's degree or Bachelor's degree (UK) in scientific fields like biology or chemestry. Excellent command of spoken and written English, communication skills as well as team spirit are essential. We are offering a competitive, interdisciplinary environment with a track record of intense mutual collaboration. In addition to the individual training-through-research our programme includes further elements such as workshops, summer schools, internships and secondments to the partners’ laboratories.

The following eligibility rules apply for participation in a Marie Skłodowska Curie Innovative Training Network:

Applicants must be in the first 4 years after obtaining their Master´s degree and/or Bachelor’s degree and must not have resided or carried out their main activity (work, studies, etc.) in the host country for more than 12 months in the 3 years immediately before the recruitment date.

In addition, local regulations of the host countries may apply. The salary is based on standard living, mobility and family allowances which are adapted to the respective country of recruitment.

 

The following positions are available:

 

ACADEMISCH ZIEKENHUIS LEIDEN (LUMC)

Principal Investigator (PI) and coordinator Dr. Alexander Vahrmeijer

 

ESR 1- Optimal watch and wait criteria needed to identify those patients with cCR.

Define imaging criteria to identify patients eligible for organ preserving strategies based on endoscopy and MRI.

 

ESR 2- PLGA platform for targeted and dual modality PET-CT and fluorescence imaging

 

UNIVERSITE’ DE STRASBOURG (STRAS)

PI- Sylvain Gioux

 

ESR 3 – Image system design and analysis

 

KAROLINKA INSTITUTET

PI – Anna Martling

 

ESR 4 – Development of quality criteria for new watch and wait centres  

 

FUNDACAO D. ANNA SOMMER CHAMPALIMAUD AND DR. CARLOS MONTEZ CHAMPALIMAUD (CCC)

PI – Nuno Figueiredo

 

ESR 5 – Clinical training in fluorescence imaging (POSITION NO LONGER AVAILABLE)

 

 

STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEWUENHOEK ZIEKENHUIS (NKI)

PI – Regina Beets-Tan

 

ESR 6 – Clinical training imaging strategies

 

 

UNIVERSITAETMEDIZIN GOETTINGEN-GEORG-AUGUST-UNIVERSITAET GOETTINGEN-STIF

 

PI – Frauke Alves

ESR 7 – Tumour and inflammation targeting under dual PET-CT and fluorescence imaging

 

 

 

 

 

 

 

THE UNIVERSITY OF LIVERPOOL (ULIV)

 

PI – Arthur Sun Myint

ESR 8 - Develop a pre-treatment decision model to inform patients and provide a structure for “shared decision making”

ESR 9 - Optimisation of localized high dose radiotherapy to treat tumour regrowth.

 

THE UNIVERSITY OF MANCHESTER (UNIMAN)

 

PI – Andrew Renehan

 

ESR 10 - Develop a pre-treatment strategy of risk assessment and benefits

 

 

UNIVERSITA’ DEGLI STUDI DI CAMERINO (UC)

 

PI – Piera Di Martino

ESR 11 – Nanoparticle incapsulation of immune reagents

 

 

PERCUROS B.V. (PERC)

 

PI – Alan Chan

 

ESR 12 – The isolation and enumeration of exosomes as material to identify rectal cancer-specific miRNA biomarkers

(POSITION NO LONGER AVAILABLE)

 

 

SIMFO SPEZIELLE IMMUNOLOGIE FORSCHUNG ENTWICKLUNG GMBH (SIMFO)

 

PI – Katharina Pachmann

 

ESR 13 - The development of a more robust CTC assay to provide dynamic information, as part of a watch and wait strategy monitoring disease status of patients

 

 

SURGIMAB SAS (SURGI)

PI – Francoise Cailler

 

ESR 14 - Process, analysis and in vivo visualization of SGM-101 and cRGD-ZW800

 

 

EDINBURGH MOLECULAR IMAGING LIMITED (EMI)

PI – Christophe Portal

 

ESR 15 - In vivo validation of EMI-137 and EMI-200

 

For more specific information about the vacancies, you can click here:

www.cast-cancer.eu

If you want to apply for one of the position please read the basic eligibility criteria first and send your application to jobs@cast-cancer.eu providing all required information (incl. the ID of the position like "CAST ESR ##" as reference).

 

 

 

 

                                                                                                  JOB LOCATIONS

 

1 position(s) available at

University of Manchester

Manchester,United Kingdom

 

1 position(s) available at Karolinska Institute, Stockholm,

Sweden

 

1 position(s) available at Universitatmedizin Goettingen-Georg-August-Universitata Goettingen-Stiftung offentlichen Rechts,

Germany

 

 

1 position(s) available at

The Netherland Cancer Institute, Rotterdam, Netherlands

 

1 position(s) available at Universite’de Strasbourg, Strasbourg,France

 

1 position(s) available at

Champalimaud Foundation,

Lisbon, Portugal

 

 

2 position(s) available at

University of Liverpool,

Liverpool,

United Kingdom

 

 

2 position(s) available at Leiden University Medical Centre, Leiden,

Netherlands

 

1 position(s) available at

University of Camerino,

Camerino, Italy

 

1 position(s) available at

Simfo GmbH,Bayreuth,

Germany

 

1 position(s) available at

Surgimab SAS

Montpellier, France

 

1 position(s) available at

Edinburgh Molecular Imaging

Edinburgh, United Kingdom

 

1 position(s) available at

Percuros B.V.,

Leiden, Netherlands

 

Disclaimer:

The responsibility for the jobs published on this website, including the job description, lies entirely with the publishing institutions.

The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.

 

Benefits

We are offering a competitive, interdisciplinary environment with a track record of intense mutual collaboration. In addition to the individual training-through-research our programme includes further elements such as workshops, summer schools, internships and secondments to the partners’ laboratories.

Eligibility criteria

The following eligibility rules apply for participation in a Marie Skłodowska Curie Innovative Training Network:

Applicants must be in the first 4 years after obtaining their Master´s degree and must not have resided or carried out their main activity (work, studies, etc.) in the host country for more than 12 months in the 3 years immediately before the recruitment date. In addition, local regulations of the host countries may apply.

Selection process

To apply for one of the positions please send the following information to jobs@cast-cancer.eu

  • your complete CV,
  • motivation letter,
  • copies of University Master certificates or equivalents,
  • contact details of two referees who can provide a letter of recommendation.

 

Please state the vacancy reference (for example: “CAST ESR 1”) in the subject line. After eligibility screening, your application will be forwarded to one of the appropriate consortium members for further evaluation.

 

 

 

Additional comments

WEBSITE FOR ADDITIONAL JOB DETAILS:

https://www.cast-cancer.eu

REQUIREMENTS

Required Research Experiences

  • RESEARCH FIELD
    Medical sciencesMedicine
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4

Offer Requirements

  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

There are strict eligibility requirements for the ESR PhD positions in MSCA-ITN. Please ensure that you qualify before applying, as ineligible candidates cannot be considered. Applicants should not have resided or performed their main activity (work, studies, etc.) in the country of the host institution for more than 12 months in the 3 year period immediately prior to the start date of the PhD research.

Applicants for the ESR PhD positions should be in the first 4 years (full-time equivalent) of their research careers and not yet have been awarded a doctorate. This 4 year period is measured from the date of obtaining the degree which would formally entitle to embark on a doctorate.

Specific Requirements

Applicants must be in the first 4 years after obtaining their Master´s degree or Bachelor's degree (depending on the host Country) and must not have resided or carried out their main activity (work, studies, etc.) in the host country for more than 12 months in the 3 years immediately before the recruitment date. In addition, local regulations of the host countries may apply.

 

To apply for one of the positions please send the following information to jobs@cast-cancer.eu

  • your complete CV,
  • motivation letter,
  • copies of University Master certificates or equivalents,
  • contact details of two referees who can provide a letter of recommendation.

 

Please state the vacancy reference (for example: “CAST ESR 1”) in the subject line. After eligibility screening, your application will be forwarded to one of the appropriate consortium members for further evaluation.

Map Information

Work location(s)
2 position(s) available at
ACADEMISCH ZIEKENHUIS LEIDEN (LUMC)
Netherlands
Leiden
2333ZA
Albinusdreef 2
1 position(s) available at
UNIVERSITE' DE STRASBOURG (STRAS)
France
Strasbourg
67081
Rue Blaise Pascal 4
1 position(s) available at
KAROLINSKA INSTITUTET (KI)
Sweden
Stockholm
17177
Nobels Vag 5
1 position(s) available at
FUNDACAO D.ANNA SOMMER CHAMPALIMAUD AND DR. CARLOS MONTEZ CHAMPALIMAUD (CCC)
Portugal
Lisbon
1400 038
Avenida Brasilia
1 position(s) available at
SICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEWUENHOEK ZIEKENHUIS (NKI)
Netherlands
Amsterdam
1066 CX
Plesmanlaan 121
1 position(s) available at
UNIVERSITAETMEDIZIN GOETTINGEN-GEORG-AUGUST-UNIVERSITAET GOETTINGENSTIF (UMG-GOE)
Germany
Goettingen
37075
Robert-Koch-Strasse 40
2 position(s) available at
THE UNIVERSITY OF LIVERPOOL (ULIV)
United Kingdom
Liverpool
L69 7ZX
Brownlow Hill 765 Foundation Building
1 position(s) available at
THE UNIVERSITY OF MANCHESTER (UNIMAN)
United Kingdom
Manchester
M13 9PL
Oxford Road
1 position(s) available at
UNIVERSITA' DEGLI STUDI DI CAMERINO (UC)
Italy
Camerino
62032
Piazza Cavour 19F
1 position(s) available at
PERCUROS B.V. (PERC)
Netherlands
Leiden
2333 BZ
Plesmanlaan 1
1 position(s) available at
SIMFO SPEZIELLE IMMUNOLOGIE FORSCHUNG ENTWICKLUNG GMBH (SIMFO)
Germany
Bayreuth
95448
1 position(s) available at
SURGIMAB SAS (SURGI)
France
Montpellier
34000
1025 Avenue Henri Becquerel, 10 Parc Club Mil
1 position(s) available at
EDINBURGH MOLECULAR IMAGING LIMITED (EMI)
United Kingdom
Edinburgh
EH16 4UX
9 Little France Road

EURAXESS offer ID: 454880

Disclaimer:

The responsibility for the jobs published on this website, including the job description, lies entirely with the publishing institutions. The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.

 

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