26/09/2019
Marie Skłodowska-Curie Actions

2 PhD students in Structural Biology (3 years)

This job offer has expired


  • ORGANISATION/COMPANY
    University of Oslo
  • RESEARCH FIELD
    Biological sciencesBiology
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    26/10/2019 21:00 - Europe/Athens
  • LOCATION
    Norway › Oslo
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/11/2019
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • MARIE CURIE GRANT AGREEMENT NUMBER
    860592

The position is part of the Innovative Training Network (ITN) “PROTON”. The network is devoted to the investigation of proton transport and proton-coupled transport. It is funded under Marie Sklodowska-Curie actions (H2020-MSCA-ITN-2019, grant agreement number: 860592).

The successful applicants will perform her/his studies and research at the the University of Oslo

It is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees.With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

Centre for Molecular Medicine Norway (NCMM) was established in 2008 and is the Norwegian node in the Nordic EMBL Partnership for Molecular Medicine. NCMM is a joint venture between the University of Oslo, Health Region South-East and the Research Council of Norway. From 2017 NCMM is merged with the Biotechnology Centre of Oslo and now has altogether 11 research groups. The overall objective of NCMM is to conduct cutting edge research in molecular medicine and biotechnology as well as facilitate translation of discoveries in basic medical research into clinical practice.

2 PhD Research Fellowships in Structural Biology and Drug Development

Job description

Two 3 year PhD fellowships are available in the Group of Structural Biology and Drug Development (Luecke group) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO).

The Group for Structural Biology and Drug Development investigates medically relevant proteins and protein complexes using biophysical, biochemical and structural approaches. The projects aim at understanding structure-function relationships with an emphasis on drug discovery. We employ a variety of biochemical and biophysical techniques (x-ray crystallography, single particle cryo electron microscopy, DSF, ITC, SPR, HDX-MS, SAXS, molecular dynamics simulations etc.). Externally funded projects include inhibitor discovery targeting the Helicobacter pylori pH acclimation system (a pH-gated urea channel and a cytoplasmic urease), and discovery of compounds that reactivate p53 cancer mutants in vitro and in vivo. Additional projects are available.

The PhD students will also benefit from career development programs offered both at UiO, the Norwegian BioCat initiative as well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.

More about the position

We seek highly motivated individuals with an excellent track record and experience in protein purification and biophysical and biochemical characterization of proteins and protein complexes. Experience in the field of structural biology techniques is an advantage. We offer stimulating environment with excellent working and social benefits. The fellowship requires admission to the PhD program at the Faculty of Medicine. The application to the PhD program must be submitted to the department no later than two months after taking up the position.

For more information see: https://www.med.uio.no/english/research/phd/application/index.html

Qualification requirements

- Applicants must hold a Master’s degree or equivalent in biochemistry, chemistry, molecular biology or a related.

- Hands-on experience with purification of proteins and assembly of protein complexes.

- Ability to independently perform experiments, analyze and interpret the results.

- Excellent interpersonal/communication skills.

- Fluent oral and written communication skills in English.

- Ability to operate as a team player in a multi-disciplinary environment.

Benefits

We offer

Salary NOK 449 400 - 505 800 per annum depending on qualifications in a position as PhD Research fellow, (position code 1017), attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

PROTON also provides mobility allowance and familiy allowance (if applicable).

Eligibility criteria

  1. Applicants must, at the date of recruitment by PROTON, be in the first four years (full-time equivalent research experience measured from the date when the researcher obtained the degree entitling him/her to embark on a doctorate) of their research careers
  2. They should not have been awarded a doctoral degree.
  3. Applicants must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting institution for more than 12 months in the 3 years immediately before the recruitment date. This excludes short stays such as holidays or compulsory national service.

 

Selection process

How to apply

The application must include cover letter statement of motivation and research interests CV (summarizing education, positions and academic work), copies of educational certificates (academic transcripts only), a complete list of publications and academic works, with a brief summary of the candidate’s contribution to each paper, list of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number). The application with attachments must be delivered in our electronic recruiting system, please follow the link “apply for this job”. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English.

Additional comments

Formal regulations

Please see the guidelines and regulations for appointments to Research Fellowships at the University of Oslo (https://www.uio.no/english/about/regulations/personnel/academic/guidelin...). According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure. The appointment may be shortened/given a more limited scope within the framework of the applicable guidelines on account of any previous employment in academic positions. The University of Oslo has an agreement for all employees (https://www.uio.no/english/for-employees/employment/work-results/agreeme...), aiming to secure rights to research results etc.

Contact information:

About the position and the project: Professor Hartmut "Hudel" Luecke, hudel@ncmm.uio.no

About administrative aspects of the application: HR adviser Ragni Indahl, ragni.indahl@ncmm.uio.no

Required Research Experiences

  • RESEARCH FIELD
    Biological sciencesBiology
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Biological sciences: Master Degree or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Good

Skills/Qualifications

  1. Applicants must, at the date of recruitment by PROTON, be in the first four years (full-time equivalent research experience measured from the date when the researcher obtained the degree entitling him/her to embark on a doctorate) of their research careers
  2. They should not have been awarded a doctoral degree.
  3. Applicants must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting institution for more than 12 months in the 3 years immediately before the recruitment date. This excludes short stays such as holidays or compulsory national service.
  4. We look for students with exceptional academic performance holding or very close to completing their Master degree in Physics, Chemistry, Biophysics, Biochemistry or closely related subjects,
  5. Knowledge of the English language is essential

Specific Requirements

  1. Experience in working with data and software for the visual of protein structures.
  2. Publications in international journals/attendance of international conferences in the following fields: structural biology, biochemistry (if applicable)
  3. Site directed mutagenesis, protein overexpression
  4. Protein purification and membrane reconstitution
  5. Soft skills: presentation skill, team working ability

Women are encouraged to apply. The recruitment committee gives preference to female candidates if they are equally qualified as male candidates.

 

Work location(s)
2 position(s) available at
Centre for Molecular Medicine
Norway
Oslo
0349
Gaustadalléen 21

EURAXESS offer ID: 449462

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