14/08/2019
Science 4 Refugees

DEVELOPING A NEW GENERATION OF BIOSAFE COMPOSITES FOR TOOTH RESTORATION - FOCUS ON BIOCOMPATIBILITY, TOXICITY AND BIODEGRADATION


  • ORGANISATION/COMPANY
    KU Leuven
  • RESEARCH FIELD
    Other
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    15/09/2019 23:59 - Europe/Brussels
  • LOCATION
    Belgium › Leuven
  • TYPE OF CONTRACT
    Permanent
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    38
  • REFERENCE NUMBER
    BAP-2019-563

Resin composite is currently the most used material in dentistry, enabling minimally invasive and nearly invisible tooth restoration. Besides nano-dustissues, there are also particular safety concerns regarding the potential release of the endocrine disruptor ‘bisphenol A’ (BPA). BPA can be present incomposites as production contaminant and/or degradation product, originating from BPA-based monomers, such as BisGMA. The latter serves as a polymerization‘cross-linker’ and is a main monomer matrix ingredient of many of today’s commercial dental composites (and other resin-based dental materials). Itsbi-aromatic BPA core imparts mechanical strength, rigidity and hydrophobicity to the composite matrix. Thanks to a recent KU Leuven research & development breakthrough, BPA-free bi-aromatic diols have been synthesized from wood and appear very promising to replace BisGMA in dental composite, with even the potential to further improve physico-mechanical properties of composite.

This multidisciplinary project, combining bioengineering technology with dental material science, aims to develop a new generation of biosafe dental composites based on bio-produced BisGMA monomer alternatives. The project involves the production as well as the biocompatibility, physico-mechanical and chemical property testing of experimental BPA-free composite formulations as compared to current dental composite material standards.

Benefits

  • Attractive 4-year full-time employment contract - continuation after the first 6 months/year is dependent upon a positive evaluation.
  • Supervision by recognized experts and access to state-of-the-art research infrastructure.
  • Highly innovative research project aiming to improve dental composite technology.
  • Training in complementary skills via participation at local and network-based events.
  • Salaried position according to the KU Leuven salary rates for PhD students.

Eligibility criteria

The candidate should be a holder of a university degree (such as ‘Master in Biomedical Sciences’, ‘Dentistry’, ‘Medicine’, ‘Biology’, ‘Bio-science Engineering’,‘Pharmacy’, etc.) and should have a particular interest in biomaterial and cellbiology research (biocompatibility, toxicity and biodegradation). The candidate must be able to work in team, as he/she will work in close collaboration with another PhD student, who will focus on biomaterial physico-mechanical and chemical property testing. The candidate is expected to conduct the project towards a PhD degree (4 years) and needs to enroll in the KU Leuven PhD program of the Biomedical Sciences Doctoral School.

Selection process

For more information please contact Prof. dr. Kirsten Van Landuyt, tel.: +32 16 33 24 38, mail: kirsten.vanlanduyt@uzleuven.be or Mr. Ben Mercelis, tel.: +3216332414, mail: benjamin.mercelis@kuleuven.be.
You can apply for this job no later than 15/09/2019 via the online application tool

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Work location(s)
1 position(s) available at
Katholieke Universiteit te Leuven
Belgium
Leuven
3000

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EURAXESS offer ID: 437288

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