12/07/2019
The Human Resources Strategy for Researchers
Science 4 Refugees

Doctoral Grant - PMSMatTrain ITN Early Stage Researcher “in-vivo neuro-MRI in animal models for multiple sclerosis”

This job offer has expired


  • ORGANISATION/COMPANY
    University of Antwerp
  • RESEARCH FIELD
    Biological sciencesOther
    ChemistryBiochemistry
    EngineeringBiomedical engineering
    EngineeringOther
    Medical sciencesOther
    NeurosciencesOther
    PhysicsBiophysics
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    15/09/2019 00:00 - Europe/Brussels
  • LOCATION
    Belgium › Antwerpen
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    38

The University of Antwerp is seeking to fill the following full-time vacancy (m/f) at the Bio-Imaging Lab, Department of Biomedical Sciences of the Faculty of Pharmaceutical, Biomedical & Veterinary Sciences:

Doctoral Grant - PMSMatTrain ITN Early Stage Researcher

“in-vivo neuro-MRI in animal models for multiple sclerosis”

Ref. No. PMSMatTrain – ESR-9

The PMSMatTrain project is funded by the European Union Horizon 2020 Programme under the Marie SkłodowskaCurie Initial Training Network for Early Stage Researchers (ESR) (H2020-MSCA-ITN-2018, Grant Agreement No. 813263). The ESR-9 position will be available from on January 2020 on a temporary basis for a maximum period of 3 years (renewable 1 year full-time employment contract upon positive evaluation).

The PMSMatTrain project focuses on gaining a comprehensive understanding of the progressive phase of multiple sclerosis (MS) from basics to translation, fully supported by eight beneficiaries (six research institutions and two SMEs). This multidisciplinary network will educate and train 15 Early Stage Researchers in device design, biomaterials, materials science, stem cell biology, in vitro, ex vivo and in vivo models of multiple sclerosis, molecular biology, in silico modelling of CSF flow, material functionalisation strategies and device validation.

Programme fellows will experience both public and private sector research & development training and will be best placed to secure employment as high calibre, innovative and well-trained graduates.

Core activities of the Bio-Imaging Lab:

The core R&D activity of the Bio-Imaging lab (https://www.uantwerpen.be/en/rg/bio-imaging-lab/) is experimental high resolution neuroMRI focusing on neurodegeneration, neuromodulation and neuroplasticity. The research is performed on rat and mouse models for different human neuropathologies and on songbirds as a model for neuroplasticity and learning. We have two 7Tesla 16 cm and one 9.4Tesla 20 cm horizontal bore in-vivo MRI scanners and a cryocoil from Bruker (Germany) and a desktop 4.7Tesla from MRSolutions (UK)). Our group has access to micro PET/SPECT/CT and BLI and advanced image processing through other UA research teams with whom we are clustered into a large UA imaging consortium EGAMI (Expert Group Antwerp Molecular Imaging https://www.uantwerpen.be/en/rg/bio-imaging-lab/collaborations/egami-imaging-consortium/)

Job description

You will develop and validate neuro-MRI tools that enable to follow up inflammation, demyelination and remyelination in animal models for MS. These tools will be applied to test the therapeutic efficacy of a novel device housing a multimodal hydrogel, to modulate inflammation, re-myelination and neuroprotection. Data will be acquired on 7T and 9,4 T Bruker scanners. The project is multidisciplinary and masters a wide range of techniques including acquiring data of dedicated animal models, and image analysis. At the University of Antwerp you will highly interact with ESR-10 who will be responsible for the molecular and cellular characterisation of inflammation, re-myelination and neuroprotection in animal models of MS, as well as upon therapeutic intervention. Internationally, you will directly interact with two or more ESRs from different participating organisations during one or more secondments abroad.

Duties and Responsibilities:

  • Prepare a Doctoral thesis in the field of Biomedical Sciences.
  • In collaboration with other consortium researchers, optimize the hydrogel holding device to allow in vivo MRI and investigate its efficacy in different in vivo models of multiple sclerosis.
  • Identify in vivo MRI candidate biomarkers of re-myelination and repair.
  • Develop protocols for the scale up of the optimised device in collaboration with research fellows in the private sector.
  • Participate in training events for researchers and Principal Investigators involved in the programme.
  • Liaise and report to the Project Manager, which includes contributing to periodic scientific reports.
  • Contribute to the reporting of project milestones and deliverables in accordance with EU deadlines.
  • Promote and disseminate results from the programme, which includes contributing to newsletters and participating in outreach events.

Qualifications: Essential

  • Master degree in Biomedical sciences, Biomedical Engineering, Bio-Engineering, Biochemistry, Physics, or related fields, obtained with outstanding or excellent study results.
  • Less than 4 years' full time-equivalent research experience and not yet have been awarded a doctoral degree (PhD).
  • Resided less than 12 months in Belgium in the last 3 years.
  • Excellent communication and organisation skills.
  • Fluent in spoken and written English.
  • Excellent writing and presentation skills.
  • Flexibility and ability to work in a team environment.
  • Availability to travel nationally and internationally two to three times a year

Qualifications: Desirable

  • Experience with outreach events.
  • A keen interest in pursuing translational research in multiple sclerosis.

Salary: The remuneration will be in line with the European Commission rules for Marie Skłodowska-Curie grant holders (Early-Stage Researchers, Initial Training Network). http://ec.europa.eu/research/participants/data/ref/h2020/wp/2018-2020/main/h2020-wp1820-msca_en.pdf.

Start date: Position is available from on January 2020.

Continuing Professional Development/Training:

  • Researchers at the University of Antwerp are encouraged to avail of a range of training and development opportunities designed to support their personal career development plans.
  • Further information on research and working at the University of Antwerp is available on https://www.uantwerpen.be/en/jobs/international-staff-office/
  • For information on moving to Belgium, please see www.euraxess.be

Additional information:

Informal enquiries concerning the post may be made to Dr. Marleen Verhoye: marleen.verhoye@uantwerpen.be

Apply:

Applications (in English) should include a CV (Please use the Europass template: https://europass.cedefop.europa.eu/editors/en/cv/compose), certificates of examination grades, a motivation letter (max. one page) describing your research career goals, skills and experience, as well as two letters of recommendation. Please send applications by e-mail (in PDF only) to Jörn Engelmann (jorn.engelmann@uantwerpen.be). Please quote the project name and reference number "Application, PMSMatTrain-ESRs-9” in the subject line of e-mail application.

Closing date for receipt of applications is September 15th, 2019.

All positions are recruited in line with Open, Transparent, Merit (OTM) and Competency based recruitment.

The University of Antwerp is a family friendly organization, with a focus on equal opportunities and diversity. Our HR-policy for researchers was awarded by the European Commission with the quality label HR Excellence in research.

This project has been funded by the European Union Horizon 2020 Programme (H2020-MSCAITN-2018) under the Marie Skłodowska-Curie Initial Training Network and Grant Agreement.

Web site for additional job details

Required Research Experiences

  • RESEARCH FIELD
    Biological sciences
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Chemistry
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Engineering
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Engineering
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Medical sciences
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Neurosciences
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Physics
  • YEARS OF RESEARCH EXPERIENCE
    None
Work location(s)
1 position(s) available at
University of Antwerp
Belgium
Antwerpen
2000
Prinsstraat 13

EURAXESS offer ID: 427169
Posting organisation offer ID: 131873

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