11/06/2019

Doctoral candidate (PhD-student) in protein biochemistry

This job offer has expired


  • ORGANISATION/COMPANY
    University of Gdansk
  • RESEARCH FIELD
    Biological sciencesOther
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    15/07/2019 23:00 - Europe/Athens
  • LOCATION
    Poland › Gdańsk
  • TYPE OF CONTRACT
    Other
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/08/2019

Hsp70/J-protein chaperones substrate binding cycle: molecular mechanisms and functional consequences

Project is carried out within the Team 4/2017 programme of the Foundation for Polish Science, the agreement no POIR.04.04.00-00-4114/17-00

Project description:

The goal of this project is to gain a better understanding of molecular characteristic of Hsp70, and its J-protein co-chaperones, that drive their specific functions in cellular processes both under physiological conditions or under stress or pathology. In our research, we will be employing a well-established J-protein/Hsp70 system functioning in iron-sulfur cluster biogenesis in mitochondria of Saccharomyces cerevisiae. Our long-term goal is to demonstrate that J-proteins are exploitable targets for disease intervention, because their specificity increases the likelihood that Hsp70 activity can be specifically manipulated in a therapeutically beneficial way.

Key responsibilities include:

1. performing research using biochemical and molecular biological techniques (independently and in collaboration with other team members)

2. participation in research design and data analysis

3. participation in preparation and writing of manuscripts

4. supervising younger researchers (Master students) involved in the project

5. active participation in lab meetings, departmental seminars and conferences

 

We offer:

-work in active research team in an excellent scientific environment

-comprehensive cross-disciplinary training in protein biochemistry, protein evolution, protein structure/function predictions

-participation in scientific seminars and conferences

-20 months of stipend (4000PLN/month)

Offer Requirements

  • REQUIRED LANGUAGES
    ENGLISH: Good

Skills/Qualifications

1. Masters degree in one of the fields: biotechnology, biology, bioinformatics

2. Solid laboratory training in protein biochemistry, including protein purification, measurements of protein-protein interactions, measurements of enzymatic activities

3. Ability to communicate fluently in English (spoken and written)

4. Strong motivation to pursue scientific questions, creativity and analytical thinking

 

Specific Requirements

Required documents:

1. Motivation letter (in English)

2. CV (in English)

3. Two signed reference letters, one must be a supervisor of the Master thesis

4. Contact information for these two referees

Work location(s)
2 position(s) available at
University of Gdansk
Poland
Gdańsk
80-307
Abrahama 58

EURAXESS offer ID: 416054

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