ORGANISATION/COMPANYCNRS-Institut de la Mer de Villefranche
RESEARCH FIELDBiological sciences › Biology
RESEARCHER PROFILEFirst Stage Researcher (R1)
APPLICATION DEADLINE23/06/2019 23:00 - Europe/Brussels
LOCATIONFrance › Villefranche-sur-Mer
TYPE OF CONTRACTTemporary
HOURS PER WEEK37.5
OFFER STARTING DATE01/10/2019
A 3-year PhD fellowship is available under the supervision of Lucas Leclère and Lionel Guidi at the Villefranche-sur‐Mer marine station in south of France. The fellowship is funded by the CNRS 80|Prime program. The framework of the PhD project is the development of the jellyfish species Pelagia noctiluca as an interdisciplinary model integrating genomics, ecology and developmental biology.
Pelagia noctiluca is an abundant, ecologically and economically relevant jellyfish species of the Mediterranean and the Atlantic Ocean. Exploitation of meta-barcoding data from the Tara expeditions showed that it plays a major role in the planktonic carbon cycle (Guidi et al. 2016 Nature). Contrary to most jellyfish, this species lives exclusively in the water column, its life cycle being simpler than most jellyfish life cycle, with juvenile medusae developing directly from planula larvae, within five days of fertilization. The life cycle can be completed in the laboratory and basic experimental methods have been developed (in-situ hybridization, immunofluorescence, embryo manipulation, egg injection) allowing reverse genetic methods to be used to analyze jellyfish development.
The PhD student, co-supervised by L Guidi and L. Leclère, will work on the analysis of transcriptomic data and the identification of genes specific to the different stages of the life cycle of Pelagia noctiluca following established pipelines (Leclère et al. 2019 Nature Ecology and Evolution).She/He will then identify in the different Tara datasets the fraction that can be attributed to the Pelagia species and perform a first characterization of the environmental niches of this species at different life cycle stages, as well as the spatial expression patterns of genes of particular interest through the life cycle. Depending on the progress of the work, the doctoral student will then address the function of one or two selected genes of interest, for instance genes implicated in suppressing the polyp stage in this species or in regulating the metabolism of particular life cycle stages.
The PhD student will be based at the IMEV (Institut de la Mer de Villefranche) and will work in a highly multidisciplinary environment between two internationally renowned laboratories (LOV: Villefranche Oceanography Laboratory & LBDV: Villefranche Developmental Biology Laboratory) parts of the CNRS and Sorbonne University. Interactions with the French National Sequencing Centre (Genoscope) in Paris and the Tara Ocean consortium are also expected.
We are looking for highly motivated candidates with interest in genomics, molecular ecology and developmental biology and keen to embrace both experimental and computational/bioinformatics approaches.
The suggested starting date is 1st October 2019. Applicants should have a Master degree or equivalent.
Lionel Guidi: email@example.com
Lucas Leclère : firstname.lastname@example.org
EURAXESS offer ID: 411718
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