04/03/2019

Research group leader (Bioinformatics Group)

This job offer has expired


  • ORGANISATION/COMPANY
    Medical Univeristy of Gdańsk
  • RESEARCH FIELD
    Biological sciences
    Computer science
    Medical sciences
  • RESEARCHER PROFILE
    Established Researcher (R3)
    Leading Researcher (R4)
  • APPLICATION DEADLINE
    15/05/2019 00:00 - Europe/Brussels
  • LOCATION
    Poland › Gdańsk
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/08/2019
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020
  • REFERENCE NUMBER
    PI/2019/2

Project title: 3P - Medicine "Mutations acquired during lifetime that lead to increased risk for human disease, with focus on cancer"

The 3P-Medicine Laboratory (personalized, preventive, precision) is a new science center specializing in research on acquired genetic mutations as risk factors for cancer and other diseases.

In the initial years of operation of the centre, researchers will primarily examine the role of post zygotic mutations (PZMs) in the development of breast cancer in women, prostate cancer in men, cancer of the colon and the bladder in both sexes, as well as Alzheimer’s disease. A part of the project will be devoted to analyses of loss of the Y chromosome in aging men, in connection with multiple outcomes. The research will aim at identification of the specific PZMs that are most relevant for susceptibility to these diseases. This will require collection of thousands of clinical samples especially for this purpose from patients at various stages of disease. The samples will be collected from blood and skin, and from malignant tumours, lymph nodes, distant metastases, and tissues unaffected by a nearby primary tumour.

Key responsibilities include:

 

1.Establishment of suitable software and hardware setup for computational needs of the IRA programme, including for data storage

2.processing, analysis and management of NGS and genotyping data

3.Implementing bioinformatic workflows using e.g. Snakemake, NextFlow

4.Automation of procedures using cluster job scheduler e.g. SLURM

5.Accounting of data, results and protocols

6. Assigning tasks to team members and creating a research schedule

7.Supporting and providing and bioinformatics assistance for the entire research team

8.Developing data analysis methods for purposes of scientific publications

 

Benefits

We offer:

1.Full-time employment contract;

2.Opportunity to work in an innovative scientific environment;

3.International cooperation with experienced researchers;

4.Administrative support, including assistance in recruiting technicians, PhD-student and post-doctoral scientists for your group;

5.Access to well-staffed core facilities;

6.Start-up package and funds allocated to running your group;

7.Access to the resources of GUMed IT, biobank of the Department of Medical Laboratory Diagnostics IT, UPPMAX (Uppsala Multidisciplinary Center for Advanced Computational Science).

8.You will be considered for a tenured faculty position at the Medical University of Gdansk, depending on a successful evaluation.

Selection process

Required documents:

1. CV;

2. Motivation letter;

3. References to at least three former or current employers /mentors. 

Please submit all above documents in a single pdf file.

Offer Requirements

Skills/Qualifications

1. PhD degree (minimum); relevant disciplines are computational biology, bioinformatics, genetics or related fields.

2. Documented work experience of NGS bioinformatics in an academic or industry setting (5+ years)

3. Publication record in NGS and cancer genomics

4. Proven experience in leveraging best practices from the genomics community

5. Linux/Unix sysadmin experience

6. Proven working knowledge of programming in Python, Perl or other scripting languages

7. Working knowledge of SQL and R

8. Ability to work in a team and manage projects and people

9. High level English, both spoken and written

10. Experience in biostatistics (preferred)

11. Demonstrated leadership ability in training and supervising a team of scientists

Work location(s)
1 position(s) available at
Medical Univeristy of Gdańsk
Poland
Gdańsk
80-211
Dębinki 7

EURAXESS offer ID: 385046

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