ORGANISATION/COMPANYThe University of Leeds
RESEARCH FIELDBiological sciences › Biological engineeringBiological sciences › BiologyChemistry › BiochemistryChemistry › Physical chemistryEngineering › Biomedical engineeringPhysics › Biophysics
RESEARCHER PROFILEFirst Stage Researcher (R1)
APPLICATION DEADLINE07/01/2019 23:00 - Europe/London
LOCATIONMultiple locations, see work locations below.
TYPE OF CONTRACTTemporary
HOURS PER WEEK37.5
EU RESEARCH FRAMEWORK PROGRAMMEH2020 / Marie Skłodowska-Curie Actions
MARIE CURIE GRANT AGREEMENT NUMBER814029
Are you keen to progress research in glycoscience at the interface between chemistry, biology and physics?
synBIOcarb is a Marie Skłodowska-Curie Innovative Training Network. It brings together 14 leading European partners in a transnational network, implementing a multidisciplinary and intersectorial research and training programme between the academic and the industrial partners in the fields of Synthetic Glycobiology.
Together, we will provide 15 Early Stage Researchers (ESR; 36 month PhD positions) with advanced scientific training in chemical synthesis, protein engineering, biophysics, cell biology and analytical device technologies that underpin the development and exploitation of glycoscience for diagnostics and targeted drug delivery. ESR will contribute to one, or more, of four thematic work packages that have been designed to progress the state of the art in Synthetic Glycobiology.
For information about the different positions, please consult the link provided for each of the projects.
- ESR1 - Engineering multimeric lectin complexes for membrane fusion (Prof Turnbull; University of Leeds, UK)
- ESR2 - Mucin-like glycocalyx modules for creating more complex artificial glycocalyxes (Prof Turnbull; University of Leeds, UK)
- ESR3 - Lectins on polymer scaffolds for superselective targeting of cancer cells (Dr Richter; University of Leeds, UK)
- ESR4 - Basic mechanisms and applications of lectin-triggered membrane fusion (Prof Römer, University of Freiburg, Germany)
- ESR5 - Crosslinking cytotoxic T cells and cancer cells with lectins to mediate cell death (Prof Römer, University of Freiburg, Germany)
- ESR6 - Engineering of neo-lectins and janus lectins (Dr Imberty, CERMAV-CNRS, France)
- ESR7 - Application of glycosyl transferases to functionalise protocells (Prof Breton, CERMAV-CNRS, France)
- ESR8 - Glycopeptide- and lecto-modules for protein and cell-lipid bilayer-arrays (Prof Blixt, University of Copenhagen, Denmark)
- ESR9 - Glyco-modulation of membranes to elucidate host-parasite interactions (Prof Blixt, University of Copenhagen, Denmark)
- ESR10 - Lectin attachment on surfaces by bioconjugation at non-canonical amino acids (Dr Wiltschi, ACIB; Austria)
- ESR11 - Lectin-drug conjugates to induce cancer cell death by drug delivery (Dr Wiltschi, ACIB; Austria)
- ESR12 - Nanotechnology-driven construction of bioanalytical devices for glycomics (Dr Tkáč, ICSAS, Slovakia)
- ESR13 - Affinity-based methods for high-throughput determination of glycosylation (Dr Katrlík, ICSAS, Slovakia)
- ESR14 - Development of a lectin kit for quality control of recombinant glycoprotein (Dr Landemarre, GLYcoDiag, France)
- ESR15 - Process development for the production of recombinant lectins in Escherichia coli (Dr Mairhofer, enGenes, Austria)
The successful candidate will participate in the network’s training activities and work placements at the laboratories of the synBIOcarb academic and industrial teams. Regular meetings and workshops within the EU-funded synBIOcarb Innovative Training Network will supplement the training and support provided at the host organisation. Practical scientific training will be complemented by a coordinated programme of industry-relevant transferable skills that will prepare the ESRs for future careers in the medical technologies sector.
This positions are for 36 months. The Early Stage Researcher will receive a Monthly Living Allowance plus a Mobility Allowance compliant with the applicable EC Marie Skłodowska-Curie Actions-ITN general conditions.
To meet the requirements of the Marie Skłodowska-Curie Innovative Training Network, you will:
- be an early stage researcher within the first four years of your research career,
- have not yet been awarded a doctoral degree (PhD), and
- have not lived or carried out your main activity (work/study) in your host country for more than 12 months during the past three years.
You will also need to meet the host University’s eligibility requirmeents to enrol on a PhD degree, including English language requirements if English is not your first language.
See the individual projects for details on the application process.
EURAXESS offer ID: 356323
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