01/11/2018
The Human Resources Strategy for Researchers

Post-doctoral Position on Bacteriophage Infection of Gram-Positive Bacteria

This job offer has expired


  • ORGANISATION/COMPANY
    CNRS
  • RESEARCH FIELD
    Biological sciencesBiological engineering
    ChemistryBiochemistry
    PhysicsBiophysics
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    22/11/2018 23:59 - Europe/Brussels
  • LOCATION
    France › GIF SUR YVETTE
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    35
  • OFFER STARTING DATE
    01/01/2019

Bacteriophage SPP1, like numerous eukaryotic viruses, establishes viral factories confined at specific locations of the host cell (J. Bacteriol. 193: 4893).

The project aims to pursue:
- the study of the bacterial cytoplasm spatial reorganization during bacteriophage infection
- the identification and caracterisation of viral proteins that hijack cellular functions and their bacterial targets. Infection at different stages of the B. subtilis cell cycle will be characterized (J. Virol. 89: 2875).

The approach is interdisciplinary, combining genetics, virus engineering and genome refactoring (e.g. Proc. Natl. Acad. Sci. USA 112: 7009), omics, and state of the art cell imaging techniques.

Study of the genetic basis of cellular and molecular mechanisms used by bacteriophages to infect the Gram-positive bacterium Bacillus subtilis.

The host team Bacteriophages of Gram-Positive Bacteria studies assembly of viral particles of tailed bacteriophages and infection of Gram-positive bacteria by these viruses (https://www.i2bc.paris-saclay.fr/spip.php?article580).
The team is associated to the Department of Virology at Institute of Integrated Biology of the Cell (http://www.i2bc.paris-saclay.fr/spip.php?article312) that provides a strong interdisciplinary environment for biological sciences research in the CNRS Campus of Gif-sur-Yvette (Paris region). The host Institute offers state of the art facilities for molecular biology, genomics, microbiology, advanced cell imaging, proteomics, and structural biology research.

Eligibility criteria

- the project is particularly suitable but not limited to candidates holding a PhD in bacterial/phage genetics, molecular biology or cell biology.
- experience in molecular biology, in bacteriology or in bacterial cell biology
- expertise in bacteriophage or in Bacillus manipulation is an asset
- knowledge of english language

Additional comments

The position is initially for 1 year, renewable.
To apply please submit your CV, a short research statement, together with the name and e-address of references before the 1st December 2018.
Starting date is after 1st January 2019.

Web site for additional job details

Required Research Experiences

  • RESEARCH FIELD
    ChemistryBiochemistry
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    PhysicsBiophysics
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Biological sciencesBiological engineering
  • YEARS OF RESEARCH EXPERIENCE
    None

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Chemistry: PhD or equivalent
    Physics: PhD or equivalent
    Biological sciences: PhD or equivalent
  • REQUIRED LANGUAGES
    FRENCH: Basic
Work location(s)
1 position(s) available at
Institut de Biologie Intégrative de la Cellule
France
GIF SUR YVETTE

EURAXESS offer ID: 351830
Posting organisation offer ID: 6067

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