27/09/2018
Marie Skłodowska-Curie Actions

Marie Sklodowska-Curie ESR - Glycan Research

This job offer has expired


  • ORGANISATION/COMPANY
    Ludger Ltd
  • RESEARCH FIELD
    ChemistryBiochemistry
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    02/11/2018 17:00 - Europe/London
  • LOCATION
    United Kingdom › Culham
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    37.5
  • OFFER STARTING DATE
    02/01/2019
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • REFERENCE NUMBER
    NanoCarbLud
  • MARIE CURIE GRANT AGREEMENT NUMBER
    814236

European Training Network Positions in H2020 ITN NanoCarb
 
A call for 15 PhD positions (Early Stage Researchers [ESRs]) is open in the recently granted Marie Curie European Training Network (MC-ETN) project NanoCarb - Glyco-Nanoparticles for Applications in Advanced Nanomedicine. NanoCarb is a multidisciplinary consortium including universities, research centres and SMEs with broad expertise ranging from nanotechnology, carbohydrate chemistry, glycoprofiling and in vitro/in vivo screening specialists. The network will develop novel and well-characterised nanomaterials with synthetic and native glycans that will be used for therapeutics and guide development of new drug delivery applications. The project will train early stage researchers at the interface of nanotechnology and glycosciences, with the overall goal of achieving a new generation of professionals in nanomedicine for a prospective career in both academia and industry. For further information on the project please go to www.nanocarb.eu

The successful candidates will benefit from an international scientific network of high-profile academic and industry partners offering state-of-the-art research facilities in nanotechnology, carbohydrate chemistry, glycoprofiling and in vitro/in vivo screening as well as career relevant training through research, courses, outreach activities, participation in seminar, and workshops. Each ESR will be supervised by an Industry-Academia supervisory team consisting of at least one supervisor from each sector. ESRs will receive an attractive salary in accordance with the MSCA regulations for Early Stage Researchers http://ec.europa.eu/research/mariecurieactions/.

Positions

Applications are invited for a PhD position on the Development of purification and modification strategies of N-type glycopeptide and glycan moieties for use as nanoparticle activity enhancers to be carried out under the supervision of Dr. Daniel Spencer at Ludger Ltd, Oxford, UK with the PhD registered with Dr Marco Monopoli at the Royal College of Surgeons in Ireland (RCSI). The project will focus on the purification of N-glycopeptides and N-glycans from natural sources in up to gram quantities. These compounds will then be modified using enzymatic techniques to incorporate 2-3 and 2-6 sialic acid linkages, including both NeuAc and NeuGc forms with O-acetylation. Additionally, modification of branched glycans to incorporate antennary fucosylation such as the sialyl-Lewis-X moiety will also be explored. Nanoparticles will be derivatised with these novel-materials.

The research project will enable the candidate to develop their experience in the fields of glyco-production, enzymology, purification techniques, surface chemistry and nanoparticle handling. During the PhD programme, the candidate will carry out secondments with academic partners.

Qualifications

• The ideal applicant will have a 1st Class Honours Bachelor’s degree or MSc degree (with minimum 2.1 honours from primary degree) in chemistry or biochemistry or a related discipline.

• Specific skills which would enhance a candidate’s application include experience in some of the following areas: glycobiology, enzymology, purification techniques. Excellent written and oral communication skills are also desired.

• For candidates who do not speak English as their first language, IELTS or equivalent English language test scores of at least 6.5 is required. Applicants who do not hold a valid English certificate at the time of the application, must indicate a clear plan with dates of how they seek to obtain the certificate.

Specific Eligibility Criteria valid at time of recruitment on the H2020 Marie Sklodowska Curie programme

• The applicants should be within the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree.

• Mobility rule: The applicants should not have resided or carried out main activity (studies, work, etc.) in the UK for more than 12 months in the 3 years prior to the recruitment date.

Application Process

Applicants must apply with the following documents. 

• Up-to-date Curriculum vitae inclusive of contact details of previous supervisors (max. 3 pages).

• Cover letter stating your motivation and suitability for the position (max. 1 page).

• Names and contact details of three referees.

The closing date for receipt of applications is 5.00 pm on Friday 2nd November 2018. All applications will be handled confidential. By submitting an application, applicants consent to their application being shared with the other principle investigators of the NanoCarb consortium for the sole purpose of the candidate recruitment. Only short-listed applications will be acknowledged. The interview process will consist of a two stage online interview.

 

Benefits

The project will train early stage researchers at the interface of nanotechnology and glycosciences, with the overall goal of achieving a new generation of professionals in nanomedicine for a prospective career in both academia and industry. For further information on the project please go to www.nanocarb.eu

The successful candidates will benefit from an international scientific network of high-profile academic and industry partners offering state-of-the-art research facilities in nanotechnology, carbohydrate chemistry, glycoprofiling and in vitro/in vivo screening as well as career relevant training through research, courses, outreach activities, participation in seminar, and workshops. Each ESR will be supervised by an Industry-Academia supervisory team consisting of at least one supervisor from each sector. ESRs will receive an attractive salary in accordance with the MSCA regulations for Early Stage Researchers http://ec.europa.eu/research/mariecurieactions/.

 

Eligibility criteria

• The ideal applicant will have a 1st Class Honours Bachelor’s degree or MSc degree (with minimum 2.1 honours from primary degree) in chemistry or biochemistry or a related discipline.

• Specific skills which would enhance a candidate’s application include experience in some of the following areas: glycobiology, enzymology, purification techniques. Excellent written and oral communication skills are also desired.

• For candidates who do not speak English as their first language, IELTS or equivalent English language test scores of at least 6.5 is required. Applicants who do not hold a valid English certificate at the time of the application, must indicate a clear plan with dates of how they seek to obtain the certificate.

Specific Eligibility Criteria valid at time of recruitment on the H2020 Marie Sklodowska Curie programme

• The applicants should be within the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree.

• Mobility rule: The applicants should not have resided or carried out main activity (studies, work, etc.) in Ireland for more than 12 months in the 3 years prior to the recruitment date.

 

Selection process

The selection process will consist of a two stage online interview process.

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Chemistry: PhD or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

• The ideal applicant will have a 1st Class Honours Bachelor’s degree or MSc degree (with minimum 2.1 honours from primary degree) in chemistry or biochemistry or a related discipline.

• Specific skills which would enhance a candidate’s application include experience in some of the following areas: glycobiology, enzymology, purification techniques. Excellent written and oral communication skills are also desired.

• For candidates who do not speak English as their first language, IELTS or equivalent English language test scores of at least 6.5 is required. Applicants who do not hold a valid English certificate at the time of the application, must indicate a clear plan with dates of how they seek to obtain the certificate.

 

Specific Requirements

Specific Eligibility Criteria valid at time of recruitment on the H2020 Marie Sklodowska Curie programme

• The applicants should be within the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree.

• Mobility rule: The applicants should not have resided or carried out main activity (studies, work, etc.) in Ireland for more than 12 months in the 3 years prior to the recruitment date.

Work location(s)
1 position(s) available at
Ludger
United Kingdom
Ludger
Culham
OX143EB
Ludger

EURAXESS offer ID: 341723

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