18/09/2018

Metabolic Inflammation in Diabetes

This job offer has expired


  • ORGANISATION/COMPANY
    Inserm
  • RESEARCH FIELD
    Biological sciences
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
    Recognised Researcher (R2)
    Established Researcher (R3)
    Leading Researcher (R4)
  • APPLICATION DEADLINE
    09/01/2019 23:59 - Europe/Brussels
  • LOCATION
    France › Paris
  • TYPE OF CONTRACT
    Permanent
  • JOB STATUS
    Full-time

Cordeliers Research Centre, Paris, France

The fully funded (2-years) postdoctoral position in type 2 diabetes, inflammation and epigenetic control is available at the Cordeliers Research Center in Paris, France (http://www.crc.jussieu.fr).

*Metabolic Inflammation in Diabetes and its Complications (Venteclef Lab)*

The group led by Dr. Nicolas Venteclef is a multi-disciplinary team with a focus on metabolism, inflammation/immunity and epigenetic regulation, in particular by coregulators and chromatin modifiers in the context of diabetes (http://www.crc.jussieu.fr/en/nicolas_venteclef_eng.html).
The research group is embedded in the University Center of Diabetes and its Complications giving access to human samples of very well phenotyped-patients.

The Venteclef lab combines molecular analyses, in vitro and in vivo approaches to connect basic research with comprehension of human diseases. We offer a dynamic, highly interactive environment and an international working atmosphere with state of the art facilities.

*Proposed Project*

Using state-of-the-art gene-editing and functional genomics/proteomics techniques, we seek to identify epigenomic pathways involved in human diabetes. The proposed project aims to investigate I.) the function of a novel chromatin modifying enzyme and II.) to unravel the cross-talk of metabolic and epigenetic regulation of macrophage activation in diabetes. You will combine metabolomics with genome-wide analyses, proteomics, and molecular- and cellular biology techniques to identify novel mechanisms involved in macrophage activation and function.

A strong background in epigenetics, metabolism and/or inflammation is desirable.
The postdoctoral research will be performed in a highly interdisciplinary and collaborative environment with world-class experts and advanced technologies and facilities, which provide unique and ideal career development opportunities for postdocs.

*Requirements:*

Applicants should have a recent Ph.D. degree (or equivalent) in molecular biology, genetics/epigenetics, metabolism and/or. Experience with high-throughput genomics/epigneomics, CRISPR screens and next-generation sequencing preparation and analysis is a relevant plus.

*Application process:*

Interested applicants should send a cover letter describing your past research experience, a curriculum vitae, and the contact information of three references to Dr. Nicolas Venteclef (Nicolas.venteclef@inserm.fr) with the subject line “Postdoc Application in Epigenetics”.
Deadline application: 1st October 2018

Offer Requirements

Skills/Qualifications

Postgraduate - Doctorate/PhD

Work location(s)
1 position(s) available at
Inserm
France
Paris

EURAXESS offer ID: 340157
Posting organisation offer ID: 654347