ORGANISATION/COMPANYUniversity of East Anglia
RESEARCH FIELDBiological sciences
RESEARCHER PROFILEFirst Stage Researcher (R1)
APPLICATION DEADLINE31/05/2018 23:00 - Europe/London
LOCATIONUnited Kingdom › Norwich
TYPE OF CONTRACTOther
Calcium is one of the most common secondary messengers involved in cell signalling in plants. A first response to a vast array of abiotic and biotic stresses includes changes in cytosolic calcium concentrations that regulate downstream processes. That so many processes seem to be governed by the change in the concentration of calcium has given rise to what has been called the calcium specificity problem: how can one ion species be responsible for conveying such diverse developmental processes and differentially active different pathways?
The aim of this PhD project is to develop a deeper understanding of how calcium signals are interpreted by cells and decoded into specific biological responses in plants. The project will focus on the calcium-dependent protein kinase signalling network in the model plant Arabidopsis thaliana, and will study the mechanism by which calcium-dependent protein kinases are regulated by calcium and how this allows the decoding of specific calcium signals.
This project will combine molecular biology, biochemistry and mathematical modelling, and will provide the student with excellent opportunities for multi-disciplinary training in plant molecular genetics and biochemical techniques, as well as computational modelling approaches.
This PhD project is offered on a self-funding basis. It is open to applicants with funding or those applying to funding sources. Details of tuition fees can be found at http://www.uea.ac.uk/study/postgraduate/research-degrees/fees-and-funding.
A bench fee is also payable on top of the tuition fee to cover specialist equipment or laboratory costs required for the research. The amount charged annually will vary considerably depending on the nature of the project and applicants should contact the primary supervisor for further information about the fee associated with the project.
EURAXESS offer ID: 286399