06/07/2017
The Human Resources Strategy for Researchers
Science 4 Refugees

Doctoral grant (BOF) area of Chronic kidney disease and vascular calcification

This job offer has expired


  • ORGANISATION/COMPANY
    University of Antwerp
  • RESEARCH FIELD
    ChemistryBiochemistry
    Medical sciencesMedicine
    Pharmacological sciencesClinical pharmacology
    Pharmacological sciencesCosmetology
    Pharmacological sciencesOther
    Pharmacological sciencesPharmacognosy
    Pharmacological sciencesPharmacy
    Pharmacological sciencesToxicology
    Pharmacological sciencesVeterinary pharmacology
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    15/08/2017 00:00 - Europe/Brussels
  • LOCATION
    Belgium › Antwerpen
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40

The Department of Biomedical sciences is seeking to fill a full-time (100%) vacancy in the Laboratory of Pathophysiology for a

Doctoral Grant by the University Research Fund (BOF) in the area of chronic kidney disease and vascular calcification

The three main research pillars of the Laboratory of Pathophysiology at the Antwerp University are renal failure, vascular calcification and aberrant bone metabolism. These three pathologies are closely interwoven as malfunction of one of the organs affects the other two. This (patho)physiological interrelation is of great clinical and therapeutic importance in patients with chronic kidney disease. The research of our lab focuses on understanding this pathophysiological link as well as the underlying cellular and molecular mechanisms in the respective organs with the ultimate aim to develop and evaluate new treatment strategies.

Project description

Chronic kidney disease (CKD) is a world-wide recognized public health problem affecting 8–16% of the world population and represents a progressive loss of renal function over a period of months or years ultimately leading to end stage renal disease (CKD stage 5) which inevitably requires renal replacement therapy, i.e. dialysis or kidney transplantation. CKD also confers a markedly increased risk of cardiovascular disease (mainly vascular calcification) which accounts for 50% of all deaths in this population.

Current treatment strategies for bot CKD and vascular calcification mainly focus on controlling important risk factors, however to date, effective treatment directly targeting the kidney and/or the vessels is lacking.

Therefore the current project aims to investigate the possibility to use metformin in the treatment and prevention of CKD and its most important complication vascular calcification. Metformin is the optimal first-line drug for type 2 diabetes mellitus and recent data from preclinical and clinical studies are pointing towards a putative beneficial impact of metformin on the kidney and cardiovascular system.

Job description

  • You prepare a doctoral thesis in the above described field.
  • You publish scientific articles related to the research project of the assignment.
  • You contribute to training of last year students in the Laboratory of Pathophysiology.

Profile and requirements

  • You hold a master degree in biomedical sciences, biochemistry, medicine, pharmaceutical sciences or any related discipline.
  • You can submit outstanding academic results.
  • Students in the final year of their degree can also apply.
  • Foreign candidates are encouraged to apply.
  • Your academic qualities comply with the requirements stipulated in the university’s policy.
  • You are highly motivated, flexible, quality-oriented, conscientious, creative and cooperative.
  • You have have good communication skills in spoken and written English.

We offer

  • a doctoral scholarship for a period of two years, with the possibility of renewal for a further two-year period after positive evaluation;
  • the start date of scholarship will be 1 October, 1 November or 1 December 2017 or 1 January 2018;
  • a gross monthly grant ranging from € 2.280,27 - € 2.419,84;
  • a dynamic and stimulating work environment.

How to apply?

  • Applications may only be submitted online until the closing date 15 August 2017 and should include a copy of your CV and a cover letter.
  • A pre-selection will be made from amongst the submitted applications.
  • The remainder of the selection procedure is specific to the position and will be determined by the selection panel.
  • The interviews of the candidates, preselected by a selection panel, will take place from 21 August until 15 September 2017.
  • More information about the application form can be obtained from vacatures@uantwerpen.be.
  • For questions about the profile and the description of duties, please contact Prof A. Verhulst (anja.verhulst@uantwerpen.be).

The University of Antwerp is a family friendly organization, with a focus on equal opportunities and diversity. Our HR-policy for researchers was awarded by the European Commission with the quality label HR Excellence in research

We support the Science4Refugees initiative and encourage asylum-seeking, refugee scientists and researchers to apply for a job at the University of Antwerp.

 

Web site for additional job details

Required Research Experiences

  • RESEARCH FIELD
    Chemistry
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Medical sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Pharmacological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Pharmacological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Pharmacological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Pharmacological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Pharmacological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Pharmacological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
  • RESEARCH FIELD
    Pharmacological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4
Work location(s)
1 position(s) available at
University of Antwerp
Belgium
Antwerpen
2000
Prinsstraat 13

EURAXESS offer ID: 234395
Posting organisation offer ID: 102795

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