13/03/2017

Chemical topography of metal-associates allergens on non-planar everyday items

This job offer has expired


  • ORGANISATION/COMPANY
    Justus-Liebig-University, Giessen
  • RESEARCH FIELD
    ChemistryInorganic chemistry
    ChemistryOrganic chemistry
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    01/05/2017 18:00 - Europe/Brussels
  • LOCATION
    Germany › Giessen
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/10/2017

Metal-organic allergens on surfaces of objects of daily use, such as jewelry or coins, are of increasing relevance in multiple dermatologic problems. The chemistry behind the formation and reaction of metal-associated allergens is widely unexplored. Complexes of nickel, copper and tin are known to be easily formed through contact of metal alloys with ubiquitous organic compounds from, e.g., skin secretions. The project aims to investigate the structure, occurence, and reactivity of typical organic reactants and of formed metal complexes on the three-dimensional surface of jewelry, decoration and coins, using atmopsheric-pressure matrix-assisted laser desorption/ionization mass spectrometry. The influence of topographic effects shall be described by the use of 3D-surface mass spectrometry imaging techniques on the micrometer scale, uniquely available at the Giessen labs. The chemistry of complex formation will be studied in vitro by organometallic synthesis, and their spontaneous formation on real objects will be simulated.

Applicants may choose between different interdisciplinary research sections: Neurosciences; Chemical Design and Analysis of Molecular Systems. A Master´s degree or equivalent is required for admission. Prospective research projects, names of supervisors and other information necessary for application can be found at:

http://www.uni-giessen.de/ggl/overview/application

Please submit your application using our online system before July 22, 2018. Please direct any enquiries concerning the online application procedure to the GGL office@ggl.uni-giessen.de.

Offer Requirements

  • REQUIRED LANGUAGES
    ENGLISH: Good

Skills/Qualifications

Creative thinking and English writing skills; solid training in inorganic, organic and analytical chemistry; interest in development and application of scientific instruments, of chemical synthesis and of powerful software tools; interest in mass spectrometry, coordination chemistry, medicinal chemistry.

 

Work location(s)
1 position(s) available at
Justus Liebig University
Germany
Giessen
35392
Leihgesterner Weg 52

EURAXESS offer ID: 189032