Postodctorant researcher (M/F)

The postdoc will be part of the team "Circulating tumor cells and tumor progression" led by Prof. Hofman at the Institut de Recherche contre le Cancer et le Vieillissement de Nice (IRCAN). He/she will work on a project to study translational regulation and development of new type of immunotherapies.
The details of the project will be discussed directly with the applicant. He/she will work under the supervision of INSERM researcher Patrick Brest (72 publications, H-index 29, including Nature Genetics, Nucleic Acid Research, Cancer Research, Autophagy, Trends in Genetics, Cells...) in collaboration with other team members in the framework of a project supported by the “Institut du Cancer (INCA)”.

The postdoc will be responsible for participating in the project consisting in the the determination of the role of p-Bodies (membraneless biocondensates) in the tumoral progression. He/she will lead the design, planning, execution and evaluation of different experiments (Western blot, immunostaining, microscopy, FIJI analysis, cell culture, molecular biology). He/she must be familiar with the relevant literature. He/she must be able to communicate results within the team, the institute and with coworkers. He/she must be able to work independently as well as with other team members and collaborators as the project evolves.

ur team is multidisciplinary with 3 PU-PH, 2 MCU, 2 PH, 4 CNRS or INSERM researchers, 1 postdoc, 5 thesis students, 4 masters, 3 Engineers and technicians to make a direct link between biology and the clinic. Our laboratory is part of IRCAN INSERM U1081 / CNRS 7284 hosted by the Antoine Lacassagne Center for Cancer Research located in Nice, France.
Aging is usually perceived as a process that results from the combined influence of constitutional or so-called « genetic » factors, life-style associated factors and external events. Understanding these multiple interconnections requires synergy between many areas of molecular, cellular or biomedical experimental biology or biology, more dedicated to the study of aging and age-related diseases such as cancer. To this goal, the Institute for Research on Cancer and Aging Nice (IRCAN UMR7284, U1081) was created on January 1st, 2012, by the University of Nice Sophia Antipolis (UNS), the National Institute for Health and Medical Research (Inserm), and the National Center for Scientific Research (CNRS). The IRCAN was established to develop a strong research center focusing on cancer and aging, in the Medical School of Nice and in partnership with the cancer “Center Antoine Lacassagne” (CAL) and the Nice University Hospital (CHUN).
The research carried out at the IRCAN involves major areas of biology, from basic research to medical applications, with the objectives of improving our understanding of the common foundation between aging and cancer, and developing innovative strategies to prevent and cure cancer and chronic age-related pathologies.
Our laboratory is made up of about fifteen people and we work in a dynamic and international environment. The candidate will also benefit from the scientific environment (around 15 teams and 100 people dedicated to research on cancer and aging) and the technical platforms made available by IRCAN.