Team leader

This job offer has expired

    Biological sciences
    First Stage Researcher (R1)
    Recognised Researcher (R2)
    Established Researcher (R3)
    Leading Researcher (R4)
    30/09/2017 23:59 - Europe/Brussels
    France › PARIS

Our research unit is made up of 6 internationally recognized research teams for a total of about 180 members and students wich provide an outstanding environment for clinical, translational and basic research. Our research unit is located in Paris at La Pitié Salpétrière Hospital, the largest hospital in Europe. Head of unit : Stéphane Hatem.

Our complementary interests include genetics, genomics, molecular and cellular biology, physiology and pharmacology to bear upon cardiovascular diseases.

All our teams have access to unique housed technological core facilities dedicated to preclinical cardiovascular and metabolical exploration : cellular and clinical imaging, animal core facilities, lipidomic, metabolomic, flow cytometry, post genomic platforms, stem cells and progenitors, L1 and L2 containment laboratories.

Our research unit is funded by the French National Institute of Health and Medical Research (INSERM) and the Pierre and Marie Curie University (UPMC). Our research laboratory is part of one of the six translational research institutes created in France in 2011. The aim of this institute is to foster the transfer of research knowledge from academic to clinic and industry (IHU Ican : http://www.ican-institute.org/).

We are seeking for :
-an established French research team
-a talented young team leader (no restriction on citizenship), funded by ATIP/Avenir Program (https://aviesan.fr/en/aviesan/accueil/programme-atip-avenir)
-ERC laureates

If you share our research unit’s dedication to excellence and innovative science, please contact stephane.hatem@upmc.fr, propose a research program (5 pages at most) and include : CV, list of publications, group composition, short description of previous achievments, 2 letters of recommendation

Application deadline : September 2017 30th
Audition and seminar of short-listed candidates : December 2017
Result of the selection : January 2018 We are seeking for a team leader

• Suffee N, Moore-Morris T, Farahmand P, Rücker-Martin C, Dilanian G, Fradet M, Sawak D, Derumeaux G,LePrince P,Clément K, Dugail I, Puceat M, Hatem SN. Atrial natriuretic peptide regulates adipose tissue accumulation in adult atria. Proc Natl Acad Sci U S A,. 2017 Jan 17. pii: 201610968.
• Dierick F, Hery T, Hoareau-Coudert B, Mougenot N, Monceau V, Claude C, Crisan M, Besson V, Dorfmüller P, Marodon G, Fadel E, Humbert M, Yaniz-Galende E, Hulot JS, Marazzi G, Sassoon D, Soubrier F, Nadaud S. Resident PW1+ Progenitor Cells Participate in Vascular Remodeling During Pulmonary Arterial Hypertension. Circ Res. 2016 Jan 12.
• Eichel CA, Beuriot A, Chevalier MY, Rougier JS, Louault F, Dilanian G, Amour J, Coulombe A, Abriel H, Hatem SN, Balse E. Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circ Res. 2016 Aug 5;119(4):544-56.
• Gautier EL, Ivanov S, Williams JW, Huang SC, Marcelin G, Fairfax K, Wang PL, Francis JS, Leone P, Wilson DB, Artyomov MN, Pearce EJ, Randolph GJ.Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. J Exp Med. 2014 Jul 28;211(8):1525-31.
• Saib A, Payot L, Kerneis M, Barthelemy O, Collet JP, Le Feuvre C, Helft G, Choussat R, Silvain J, Montalescot G.TCT-160 Impact of admission during ON vs. OFF hours in unselected ST-Elevation Myocardial Infarction Patients treated with Primary Percutaneous Coronary Intervention. J Am Coll Cardiol. 2016 Nov 1;68(18S):B65-B66
• Villard E, Perret C, Gary F, Proust C, Dilanian G, Hengstenberg C, Ruppert V, Arbustini E, Wichter T, Germain M, Dubourg O, Tavazzi L, Aumont MC, DeGroote P, Fauchier L, Trochu JN, Gibelin P, Aupetit JF, Stark K, Erdmann J, Hetzer R, Roberts AM, Barton PJ, Regitz-Zagrosek V; Cardiogenics Consortium., Aslam U, Duboscq-Bidot L, Meyborg M, Maisch B, Madeira H, Waldenström A, Galve E, Cleland JG, Dorent R, Roizes G, Zeller T, Blankenberg S, Goodall AH, Cook S, Tregouet DA, Tiret L, Isnard R, Komajda M, Charron P, Cambien F. A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. Eur Heart J. 2011 May;32(9):1065-76

Additional comments

-Genomic of cardiovascular diseases. Strong interface with the cardiology clinical department a national reference center for hereditary cardiac diseases - - Basic cardiac electrophysiology. The group is leader in ion channel trafficking and macromolecular complex organization at the plasma membrane of cardiomyocytes - - Pathophysiology of atrial fibrillation. Study the cross talk between adipose tissue and atrial myocardium and its role in the formation of the arrhythmogenic substrate - - Pharmacology of atherothrombosis - - Role of mononuclear phagocytes in immuno-metabolism. In vivo experimental approaches investigating the rôle of dendritic cells and kuppfer cells in cardiometabolic diseases. - - Cellular and vascular lipid homeostasis. Deciphering mechanisms through which bioactive lipids control cell activation and biological activities of lipoproteins with a special emphasis on the impact of nutritional challenges.

Work location(s)
1 position(s) available at

EURAXESS offer ID: 181572
Posting organisation offer ID: 86042