28/11/2016
Marie Skłodowska-Curie Actions

DOCTORAL STUDENT POSITION (Early Stage Researcher)

This job offer has expired


  • ORGANISATION/COMPANY
    University of Padova
  • RESEARCH FIELD
    ChemistryOther
    Pharmacological sciencesPharmacy
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    16/06/2017 12:00 - Europe/Brussels
  • LOCATION
    Italy › Padova
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    03/07/2017
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • REFERENCE NUMBER
    3130
  • MARIE CURIE GRANT AGREEMENT NUMBER
    722717

The Doctoral Course of Molecular
Sciences of  the University of Padova invites applications for the OCUTHER
- European Training Network within Marie Sklodowska Curie Programme:

DOCTORAL STUDENT POSITION
(Early Stage Researcher 10: Supramolecular bioconjugates for ocular delivery)

To date there is an unmet need
of effective drug delivery systems for the retina targeting that can replace
repeated and invasive intravitreal injections currently used for the treatment
of several invalidating ocular diseases.  In this regard, UNIPD intends to
design and develop novel suparamolecular systems, namely drug-polymer
bioconjugates, with specific biopharmaceutical features. A few drug-polymer
conjugates will be developed by using different polymers, different
architectures and different conjugation chemistries in order to identify the
key factors that control the biopharmaceutical behavior of the system and
affect the therapeutic performance in the treatment of the eye diseases.
Bioconjugates will be characterized by an array of analytical tools (NMR, IR,
mass spectrometry, DLS, viscosimetry). The biopharmaceutical profile of the
bioconjugates will be investigated to assess drug release and intracellular
drug delivery in vitro. The PhD thesis project will allow for understanding the
molecular requirements for nanocarriers  diffusivity and cell interfacing
features in the retinal environment.

Required background: MSc degree in an appropriate field of science (e.g. medicinal chemistry,
chemistry, material sciences, polymer chemistry, advanced drug delivery).

The Advanced Drug Delivery
research unit led by Paolo Caliceti and Stefano Salmaso at the Department of
Pharmaceutical and Pharmacological Sciences of the University of Padova, Italy,
offers a multi-disciplinary training program in the field of pharmaceutical
sciences. The group is recognized in the field of advanced and responsive drug
delivery systems both for small drugs and therapeutic macromolecules
(oligonucleotides and proteins). The research is aimed at developing new novel
supramolecular  nanomedicines designed for spatially and timely controlled
drug delivery, namely  functional colloidal carriers for ocular drug
delivery. Research activity in the group involves the design and synthesis of
functional components, set-up of novel bioconjugation procedures, physical and
chemical combination of the functional materials into colloidal carriers
(typically liposomes and micelles) to tailor their behavior within the
microenvironment. The  physico-chemical profiling, biopharmaceutical
features and biological performance of the novel formulations are characterized
by means of a variety of analytical technologies. The OCUTHER network will
provide training across a wide range of disciplines including biology,
pharmacology, chemistry, drug delivery, nanopharmacy and ophthalmology,
ensuring interdisciplinary and inter-sectorial learning experience. The
candidate selected for the Initial Training Network (ITN) project OCUTHER will
be enrolled in the Molecular Sciences doctoral program of the University of Padova.
The PhD program includes secondments in the laboratories of OCUTHER partners.

Eligibility criteria

Your application should include (and be limited to) the following attachments:

  • Letter of motivation.

  • Curriculum Vitae (including publications and communications if any).

  • Brief statement on how you will contribute to this project

  • Your Master of Science degree and/or official transcripts (in English).

     

Selection process

Face-to-face interviews

Web site for additional job details

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Chemistry: Master Degree or equivalent
    Pharmacological sciences: Master Degree or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

MSc degree in an appropriate field of science (e.g. medicinal chemistry, chemistry, bioconjugates, polymer chemistry, advanced drug delivery).

Work location(s)
1 position(s) available at
Department of Pharmaceutical and Pharmacological Sciences
Italy
Italy
Padova
35131
via F. Marzolo, 5

Open, Transparent, Merit based Recruitment procedures of Researchers (OTM-R)

Know more about it at University of Padova

Know more about OTM-R

EURAXESS offer ID: 158839

Disclaimer:

The responsibility for the jobs published on this website, including the job description, lies entirely with the publishing institutions. The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.

 

Please contact support@euraxess.org if you wish to download all jobs in XML.